Laura Lampio1, Tarja Saaresranta2, Janne Engblom3, Olli Polo4, Päivi Polo-Kantola5. 1. Sleep Research Centre, Department of Physiology, University of Turku, Turku, Finland; Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland. Electronic address: lmlamp@utu.fi. 2. Sleep Research Centre, Department of Physiology, University of Turku, Turku, Finland; Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland. 3. Department of Statistics, University of Turku, Turku, Finland. 4. Department of Pulmonary Diseases, Tampere University Hospital, Tampere, Finland. 5. Sleep Research Centre, Department of Physiology, University of Turku, Turku, Finland; Department of Obstetrics and Gynecology, Turku University Hospital, Turku, Finland.
Abstract
OBJECTIVE: This follow-up study aimed to evaluate risk factors for menopausal sleep disturbances already identifiable before menopause. METHODS: At baseline, all 81 women were premenopausal. At year-five follow-up, 27 of the women were premenopausal, 40 postmenopausal, and 14 postmenopausal and using hormone therapy. We used the Basic Nordic Sleep Questionnaire to study sleep; additional questionnaires evaluated risk factors for sleep impairment. RESULTS: Sleep quality differed only marginally between the groups. The following baseline variables were associated with impaired sleep quality at follow-up: depressive symptoms increased the risk of nocturnal awakenings (OR 1.16 (95%CI 1.02-1.32), p=0.025), morning tiredness (OR 1.22 (95%CI 1.06-1.40), p=0.007), daytime tiredness (OR 1.24 (95%CI 1.06-1.44), p=0.007) and propensity to fall asleep during work or leisure time (OR 1.18 (95%CI 1.01-1.37), p=0.036). Personal crises increased the risk of longer sleep latency (OR 5.46 (95%CI 1.13-26.32), p=0.035) and of propensity to fall asleep when not active (OR 5.41 (95%CI 1.42-20.83), p=0.014). Use of medications affecting the CNS increased the risk of worse general sleep quality (OR 11.44 (95% CI 1.07-121.79), p=0.044). Perceived impaired general health (OR 2.87 (95%CI 1.04-7.94), p=0.043) and frequent night sweats (OR 10.50 (95%CI 2.25-49.01), p=0.003) increased the risk of difficulty falling asleep. CONCLUSIONS: Various premenopausal health-related factors seem to predict poor sleep in menopausal transition. Menopause itself appears to have only minor effects. Thus, it is essential to identify high-risk women to allow timely interventions that may prevent the development of sleep disturbances at menopause.
OBJECTIVE: This follow-up study aimed to evaluate risk factors for menopausal sleep disturbances already identifiable before menopause. METHODS: At baseline, all 81 women were premenopausal. At year-five follow-up, 27 of the women were premenopausal, 40 postmenopausal, and 14 postmenopausal and using hormone therapy. We used the Basic Nordic Sleep Questionnaire to study sleep; additional questionnaires evaluated risk factors for sleep impairment. RESULTS: Sleep quality differed only marginally between the groups. The following baseline variables were associated with impaired sleep quality at follow-up: depressive symptoms increased the risk of nocturnal awakenings (OR 1.16 (95%CI 1.02-1.32), p=0.025), morning tiredness (OR 1.22 (95%CI 1.06-1.40), p=0.007), daytime tiredness (OR 1.24 (95%CI 1.06-1.44), p=0.007) and propensity to fall asleep during work or leisure time (OR 1.18 (95%CI 1.01-1.37), p=0.036). Personal crises increased the risk of longer sleep latency (OR 5.46 (95%CI 1.13-26.32), p=0.035) and of propensity to fall asleep when not active (OR 5.41 (95%CI 1.42-20.83), p=0.014). Use of medications affecting the CNS increased the risk of worse general sleep quality (OR 11.44 (95% CI 1.07-121.79), p=0.044). Perceived impaired general health (OR 2.87 (95%CI 1.04-7.94), p=0.043) and frequent night sweats (OR 10.50 (95%CI 2.25-49.01), p=0.003) increased the risk of difficulty falling asleep. CONCLUSIONS: Various premenopausal health-related factors seem to predict poor sleep in menopausal transition. Menopause itself appears to have only minor effects. Thus, it is essential to identify high-risk women to allow timely interventions that may prevent the development of sleep disturbances at menopause.
Authors: Marissa A Bowman; Christopher E Kline; Daniel J Buysse; Howard M Kravitz; Hadine Joffe; Karen A Matthews; Joyce T Bromberger; Kathryn A Roecklein; Robert T Krafty; Martica H Hall Journal: Ann Behav Med Date: 2021-06-28
Authors: Nea Kalleinen; Jenni Aittokallio; Laura Lampio; Matti Kaisti; Päivi Polo-Kantola; Olli Polo; Olli J Heinonen; Tarja Saaresranta Journal: Sleep Date: 2021-06-11 Impact factor: 5.849
Authors: Mikhail Saltychev; Juhani Juhola; Jari Arokoski; Jenni Ervasti; Mika Kivimäki; Jaana Pentti; Sari Stenholm; Saana Myllyntausta; Jussi Vahtera Journal: PLoS One Date: 2021-11-18 Impact factor: 3.240