Nobuo Sasaki1, Saeko Fujiwara2, Hidehisa Yamashita3, Ryoji Ozono4, Kazushi Teramen5, Yasuki Kihara6. 1. Health Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council, Hiroshima, Japan. Electronic address: nb7ssk7@sd6.so-net.ne.jp. 2. Health Management and Promotion Center, Hiroshima Atomic Bomb Casualty Council, Hiroshima, Japan. 3. Department of Psychiatry and Neurosciences, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan. 4. Department of General Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan. 5. Department of Internal Medicine, Mitsubishi Mihara Hospital, Mihara, Japan. 6. Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Abstract
OBJECTIVE: The aim of the present study was to investigate the impact of sleep on osteoporosis. METHODS: The study used a baseline examination of the Hiroshima Sleep and Healthcare study, which was a cross-sectional and cohort study that addressed the association of sleep habits with lifestyle-related diseases. A total of 1032 participants (25-85 years of age) who underwent health examinations were included. Sleep habits, including its timing (bed time), quantity (time in bed [TIB]), and quality, were assessed using the Pittsburgh Sleep Quality Index (PSQI). The bone stiffness index (SI), a marker of osteoporosis, was measured using quantitative ultrasound systems. RESULTS: Bed time (r = 0.065, p <0.05), TIB (r = -0.064, p <0.05), and global PSQI score (r = -0.126, p <0.0001) significantly correlated with SI. Multiple regression analyses revealed that after adjusting for age, sex, body mass index, smoking, and alcohol intake, the global PSQI score (β = -0.053, p <0.05) was significantly associated with SI, whereas bed time or TIB was not. Among each component of PSQI, sleep disturbances (β = -0.084, p <0.005) were significantly associated with SI. CONCLUSION: Poor sleep quality may be associated with osteoporosis. In particular, increased sleep disturbances may be a key factor in the association between poor sleep quality and osteoporosis.
OBJECTIVE: The aim of the present study was to investigate the impact of sleep on osteoporosis. METHODS: The study used a baseline examination of the Hiroshima Sleep and Healthcare study, which was a cross-sectional and cohort study that addressed the association of sleep habits with lifestyle-related diseases. A total of 1032 participants (25-85 years of age) who underwent health examinations were included. Sleep habits, including its timing (bed time), quantity (time in bed [TIB]), and quality, were assessed using the Pittsburgh Sleep Quality Index (PSQI). The bone stiffness index (SI), a marker of osteoporosis, was measured using quantitative ultrasound systems. RESULTS: Bed time (r = 0.065, p <0.05), TIB (r = -0.064, p <0.05), and global PSQI score (r = -0.126, p <0.0001) significantly correlated with SI. Multiple regression analyses revealed that after adjusting for age, sex, body mass index, smoking, and alcohol intake, the global PSQI score (β = -0.053, p <0.05) was significantly associated with SI, whereas bed time or TIB was not. Among each component of PSQI, sleep disturbances (β = -0.084, p <0.005) were significantly associated with SI. CONCLUSION: Poor sleep quality may be associated with osteoporosis. In particular, increased sleep disturbances may be a key factor in the association between poor sleep quality and osteoporosis.
Authors: L Cheng; H Pohlabeln; W Ahrens; P Russo; T Veidebaum; C Hadjigeorgiou; D Molnár; M Hunsberger; S De Henauw; L A Moreno; A Hebestreit Journal: Osteoporos Int Date: 2020-11-27 Impact factor: 4.507