| Literature DB >> 27822623 |
Bernhard Maisch1,2.
Abstract
In the 2015 guidelines of the European Society of Cardiology (ESC) and the American Heart Association (AHA) on infective endocarditis, the diagnostics are based on the modified Duke criteria. The diagnosis can be confirmed by a combination of micro-organisms demonstrated in culture or in situ, with the detection of valvular lesions or abscess formation by an imaging modality using echocardiography, positron emission tomography computed tomography (PET/CT), cardio-CT or nuclear medical methods. The management should be further improved by an interdisciplinary endocarditis team in a specifically designated reference center. Pharmaceutical treatment is largely unchanged and based on classical antibiotics in monotherapy or as combination therapy but for staphylococcal endocarditis, gentamycin is no longer required. As cardiac surgery is needed in 50 % of the cases during the course of the disease, the urgency for surgery depends on the extent of cardiac insufficiency, the persistence of the pathogen despite antibiotic treatment and on neurological complications.Entities:
Keywords: Antibiotic therapy; Duke criteria; Echocardiography; Endocarditis; Endocarditis team
Mesh:
Year: 2016 PMID: 27822623 DOI: 10.1007/s00059-016-4494-5
Source DB: PubMed Journal: Herz ISSN: 0340-9937 Impact factor: 1.443