Literature DB >> 27822589

Regulation of lipid metabolism via a connection between the endoplasmic reticulum and lipid droplets.

Michitaka Suzuki1.   

Abstract

Lipid droplets (LDs) are ubiquitous organelles that store and supply lipids to regulate cellular lipid homeostasis. Fatty acids are packaged as triglyceride and cholesterol ester into endoplasmic reticulum (ER) membranes to synthesize LDs. Cytosolic LDs move dynamically and interact with organelles, including other LDs. In this process, functional proteins for metabolism are also transferred to LDs. In this review, I focus on interactions between the ER and LDs related to lipid metabolism.

Entities:  

Keywords:  Endoplasmic reticulum; Lipid droplets; Lipid metabolism; Organelle interaction; Protein degradation

Mesh：

Substances：

Year:  2016        PMID： 27822589     DOI： 10.1007/s12565-016-0378-2

Source DB:  PubMed          Journal:  Anat Sci Int        ISSN： 1447-073X            Impact factor:   1.741


  7 in total

Review 1.  Biogenesis and Lipase-Mediated Mobilization of Lipid Droplets in Plants.

Authors:  Yun Ju Choi; Kseniia Zaikova; Soo-Jin Yeom; Yeong-Su Kim; Dong Wook Lee
Journal:  Plants (Basel)       Date:  2022-05-05

2.  Statins Lower Lipid Synthesis But Promote Secretion of Cholesterol-Enriched Extracellular Vesicles and Particles.

Authors:  Yundi Chen; Yongrui Xu; Jing Wang; Peter Prisinzano; Yuhao Yuan; Fake Lu; Mingfeng Zheng; Wenjun Mao; Yuan Wan
Journal:  Front Oncol       Date:  2022-05-12       Impact factor: 5.738

3.  Mesoderm-specific transcript localization in the ER and ER-lipid droplet interface supports a role in adipocyte hypertrophy.

Authors:  Igor Prudovsky; Rea P Anunciado-Koza; Chester G Jacobs; Doreen Kacer; Matthew E Siviski; Robert A Koza
Journal:  J Cell Biochem       Date:  2017-12-04       Impact factor: 4.429

4.  Diet normalization or caloric restriction as a preconception care strategy to improve metabolic health and oocyte quality in obese outbred mice.

Authors:  Anouk Smits; Waleed F A Marei; Diane De Neubourg; Jo L M R Leroy
Journal:  Reprod Biol Endocrinol       Date:  2021-11-04       Impact factor: 5.211

5.  FGF21 Reduces Lipid Accumulation in Bovine Hepatocytes by Enhancing Lipid Oxidation and Reducing Lipogenesis via AMPK Signaling.

Authors:  Yezi Kong; Chenxu Zhao; Panpan Tan; Siqi Liu; Yan Huang; Fangyuan Zeng; Pingjun Ma; Yazhou Guo; Baoyu Zhao; Jianguo Wang
Journal:  Animals (Basel)       Date:  2022-04-06       Impact factor: 2.752

6.  Lipid droplets in granulosa cells are correlated with reduced pregnancy rates.

Authors:  Shira Raviv; Shay Hantisteanu; Shilhav Meisel Sharon; Yuval Atzmon; Mediea Michaeli; Einat Shalom-Paz
Journal:  J Ovarian Res       Date:  2020-01-06       Impact factor: 4.234

Review 7.  Caveolin-1 Regulates Cellular Metabolism: A Potential Therapeutic Target in Kidney Disease.

Authors:  Shilu Luo; Ming Yang; Hao Zhao; Yachun Han; Na Jiang; Jinfei Yang; Wei Chen; Chenrui Li; Yan Liu; Chanyue Zhao; Lin Sun
Journal:  Front Pharmacol       Date:  2021-12-10       Impact factor: 5.810
  7 in total

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