| Literature DB >> 27822230 |
Masaya Takahashi1, Shoichiro Taniuchi1, Kazuhiko Soejima1, Yasuko Hatano1, Sohsaku Yamanouchi1, Kazuanri Kaneko1.
Abstract
[This corrects the article DOI: 10.1186/s13223-016-0150-0.].Entities:
Year: 2016 PMID: 27822230 PMCID: PMC5088668 DOI: 10.1186/s13223-016-0160-y
Source DB: PubMed Journal: Allergy Asthma Clin Immunol ISSN: 1710-1484 Impact factor: 3.406
The rate of desensitization and 2-weeks-sustained unresponsiveness for cow’s milk allergy in the oral immunotherapy group and the untreated group
| OIT (N = 31) | Untreated group (N = 17) | ||
|---|---|---|---|
| Desensitization | Two-weeks-sustained unresponsiveness | Pass OFC | |
| At 1-year follow-up | 14/31 (45 %)*, # | 7/31 (21 %)**, ## | 0/17 (0 %)*,**, a |
| At 2-year follow-up | 18/30 (60 %)# | 14/30 (47 %)## | |
| At 3-year follow-up | 21/30 (70 %) | 16/30 (53 %) | |
| At 4-year follow-up | 17/20 (85 %) | 14/20 (70 %) | |
OIT oral immunotherapy, OFC open food challenge
* P = 0.002 by Fisher’s exact test
** P = 0.036 by Fisher’s exact test
# P = 0.025 by Wilcoxon signed rank test
## P = 0.008 by Wilcoxon signed rank test
aPatients in untreated groups continued complete elimination of cow’s milk and a year later were performed open food challenge using fresh cow’s milk was performed
Fig. 1Study enrollment and outcomes of OIT oral immunotherapy with CM cow’s milk. (Hash) After the achievement of 2-weeks-sustained unresponsiveness, the patients are followed for 2–3 year and they are able to ingest CM and CM products freely without any adverse events. OFC open food challenge