Literature DB >> 27821993

Mesenchymal stromal cells in spinal fusion: Current and future applications.

Adam E M Eltorai1, Cynthia J Susai1, Alan H Daniels2.   

Abstract

Mesenchymal stromal cells (MSCs) have been a promising area of study for regenerative medicine. These cells can be harvested from bone marrow, adipose tissue, and other areas allowing for autologous transplantation of these cells into the area of degeneration or injury. With the proper signals, these cells may be able to regenerate healthy tissue. Recent studies have yielded promising evidence supporting translational mesenchymal stromal cell applications particularly in spinal fusion surgery.

Entities:  

Keywords:  Mesenchymal stromal cells; Spine fusion; Spine surgery; Stem cells

Year:  2016        PMID： 27821993      PMCID： PMC5090226          DOI： 10.1016/j.jor.2016.10.010

Source DB:  PubMed          Journal:  J Orthop        ISSN： 0972-978X


  38 in total

Review 1.  Cell technologies for spinal fusion.

Authors:  Francis H Shen; Dino Samartzis; Howard S An
Journal:  Spine J       Date:  2005 Nov-Dec       Impact factor: 4.166

2.  Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells.

Authors:  Kotaro Yoshimura; Katsujiro Sato; Noriyuki Aoi; Masakazu Kurita; Keita Inoue; Hirotaka Suga; Hitomi Eto; Harunosuke Kato; Toshitsugu Hirohi; Kiyonori Harii
Journal:  Dermatol Surg       Date:  2008-05-29       Impact factor: 3.398

3.  Human adipose tissue is a source of multipotent stem cells.

Authors:  Patricia A Zuk; Min Zhu; Peter Ashjian; Daniel A De Ugarte; Jerry I Huang; Hiroshi Mizuno; Zeni C Alfonso; John K Fraser; Prosper Benhaim; Marc H Hedrick
Journal:  Mol Biol Cell       Date:  2002-12       Impact factor: 4.138

4.  Influence of smoking on spinal fusion after spondylodesis surgery: A comparative clinical study.

Authors:  Pia C Hermann; Markus Webler; Rahel Bornemann; Tom R Jansen; Yorck Rommelspacher; Kirsten Sander; Philip P Roessler; Sönke P Frey; Robert Pflugmacher
Journal:  Technol Health Care       Date:  2016-09-14       Impact factor: 1.285

5.  Genetically modified mesenchymal stem cells induce mechanically stable posterior spine fusion.

Authors:  Dima Sheyn; Martin Rüthemann; Olga Mizrahi; Ilan Kallai; Yoram Zilberman; Wafa Tawackoli; Linda E A Kanim; Li Zhao; Hyun Bae; Gadi Pelled; Jess G Snedeker; Dan Gazit
Journal:  Tissue Eng Part A       Date:  2010-09-28       Impact factor: 3.845

6.  BMP-6 is more efficient in bone formation than BMP-2 when overexpressed in mesenchymal stem cells.

Authors:  O Mizrahi; D Sheyn; W Tawackoli; I Kallai; A Oh; S Su; X Da; P Zarrini; G Cook-Wiens; D Gazit; Z Gazit
Journal:  Gene Ther       Date:  2012-06-21       Impact factor: 5.250

7.  Transpedicular aspiration of osteoprogenitor cells from the vertebral body: progenitor cell concentrations affected by serial aspiration.

Authors:  Robert F McLain; Cynthia A Boehm; Candace Rufo-Smith; George F Muschler
Journal:  Spine J       Date:  2009-12       Impact factor: 4.166

8.  A retrospective study of iliac crest bone grafting techniques with allograft reconstruction: do patients even know which iliac crest was harvested? Clinical article.

Authors:  Stephen M Pirris; Eric W Nottmeier; Sherri Kimes; Michael O'Brien; Gazanfar Rahmathulla
Journal:  J Neurosurg Spine       Date:  2014-07-11

9.  Proinflammatory Mediators Enhance the Osteogenesis of Human Mesenchymal Stem Cells after Lineage Commitment.

Authors:  Michiel Croes; F Cumhur Oner; Moyo C Kruyt; Taco J Blokhuis; Okan Bastian; Wouter J A Dhert; Jacqueline Alblas
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

Review 10.  Spinal fusion in the next generation: gene and cell therapy approaches.

Authors:  Marta Barba; Claudia Cicione; Camilla Bernardini; Vincenzo Campana; Ernesto Pagano; Fabrizio Michetti; Giandomenico Logroscino; Wanda Lattanzi
Journal:  ScientificWorldJournal       Date:  2014-01-28
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  4 in total

1.  Cell therapies for chondral defects of the talus: a systematic review.

Authors:  Filippo Migliorini; Jörg Eschweiler; Christian Goetze; Torsten Pastor; Riccardo Giorgino; Frank Hildebrand; Nicola Maffulli
Journal:  J Orthop Surg Res       Date:  2022-06-11       Impact factor: 2.677

Review 2.  History of Bone Grafts in Spine Surgery.

Authors:  Gilad A Hampel; Emre Yilmaz; Chrissie Massrey; William Clifton; Joe Iwanaga; Marios Loukas; R Shane Tubbs
Journal:  Cureus       Date:  2022-05-01

3.  Overexpression of miR-21 in stem cells improves ovarian structure and function in rats with chemotherapy-induced ovarian damage by targeting PDCD4 and PTEN to inhibit granulosa cell apoptosis.

Authors:  Xiafei Fu; Yuanli He; Xuefeng Wang; Dongxian Peng; Xiaoying Chen; Xinran Li; Qing Wang
Journal:  Stem Cell Res Ther       Date:  2017-08-14       Impact factor: 6.832

4.  Allogenic Stem Cells in Spinal Fusion: A Systematic Review.

Authors:  Patrick C Hsieh; Zorica Buser; Andrea C Skelly; Erika D Brodt; Darrel Brodke; Hans-Joerg Meisel; Jong-Beom Park; S Tim Yoon; Jeffrey C Wang
Journal:  Global Spine J       Date:  2019-05-08
  4 in total

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