Literature DB >> 2782182

How phosphocreatine buffers cyclic changes in ATP demand in working muscle.

C Funk1, A Clark, R J Connett.   

Abstract

1. Spatial buffering is hardly necessary for maintaining ATP concentration. 2. Temporal buffering may be essential to defend concentration of products of ATP hydrolysis. ADP would vary 4-fold and AMP would vary 16-fold during a single twitch without buffering. 3. The principal function of the transphosphorylating reaction may be to buffer temporally the concentrations of controlling reactants.

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Year:  1989        PMID: 2782182     DOI: 10.1007/978-1-4684-5643-1_76

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  5 in total

Review 1.  Metabolic factors in fatigue.

Authors:  K Sahlin
Journal:  Sports Med       Date:  1992-02       Impact factor: 11.136

2.  Mechanisms underlying reduced maximum shortening velocity during fatigue of intact, single fibres of mouse muscle.

Authors:  H Westerblad; A J Dahlstedt; J Lännergren
Journal:  J Physiol       Date:  1998-07-01       Impact factor: 5.182

Review 3.  Domestication of the cardiac mitochondrion for energy conversion.

Authors:  Robert S Balaban
Journal:  J Mol Cell Cardiol       Date:  2009-03-02       Impact factor: 5.000

Review 4.  Perspectives on: SGP symposium on mitochondrial physiology and medicine: metabolic homeostasis of the heart.

Authors:  Robert S Balaban
Journal:  J Gen Physiol       Date:  2012-06       Impact factor: 4.086

Review 5.  Energy metabolism design of the striated muscle cell.

Authors:  Brian Glancy; Robert S Balaban
Journal:  Physiol Rev       Date:  2021-03-18       Impact factor: 46.500

  5 in total

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