Literature DB >> 27820795

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.

Pedro F Teixeira1, Beata Kmiec1, Rui M M Branca2, Monika W Murcha3, Anna Byzia4, Aneta Ivanova3, James Whelan5, Marcin Drag4, Janne Lehtiö2, Elzbieta Glaser1.   

Abstract

Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.

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Year:  2016        PMID: 27820795     DOI: 10.1038/nchembio.2227

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


  5 in total

1.  Autocatalytic Processing and Substrate Specificity of Arabidopsis Chloroplast Glutamyl Peptidase.

Authors:  Nazmul H Bhuiyan; Elden Rowland; Giulia Friso; Lalit Ponnala; Elena J S Michel; Klaas J van Wijk
Journal:  Plant Physiol       Date:  2020-07-06       Impact factor: 8.340

2.  The Evolutionary History of Peptidases Involved in the Processing of Organelle-Targeting Peptides.

Authors:  Clotilde Garrido; Francis-André Wollman; Ingrid Lafontaine
Journal:  Genome Biol Evol       Date:  2022-07-02       Impact factor: 4.065

Review 3.  Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants.

Authors:  Abi S Ghifari; Monika W Murcha
Journal:  Biochem Soc Trans       Date:  2022-06-30       Impact factor: 4.919

4.  Wastewater effluent affects behaviour and metabolomic endpoints in damselfly larvae.

Authors:  Jana Späth; Jerker Fick; Erin McCallum; Daniel Cerveny; Malin L Nording; Tomas Brodin
Journal:  Sci Rep       Date:  2022-04-26       Impact factor: 4.996

Review 5.  Peptidome: Chaos or Inevitability.

Authors:  Irina Lyapina; Vadim Ivanov; Igor Fesenko
Journal:  Int J Mol Sci       Date:  2021-12-04       Impact factor: 5.923

  5 in total

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