Carolina Bigert1, Per Gustavsson, Kurt Straif, Dirk Taeger, Beate Pesch, Benjamin Kendzia, Joachim Schüz, Isabelle Stücker, Florence Guida, Irene Brüske, Heinz-Erich Wichmann, Angela C Pesatori, Maria Teresa Landi, Neil Caporaso, Lap Ah Tse, Ignatius Tak-Sun Yu, Jack Siemiatycki, Jérôme Lavoué, Lorenzo Richiardi, Dario Mirabelli, Lorenzo Simonato, Karl-Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardón, David Zaridze, John K Field, Andrea 't Mannetje, Neil Pearce, John McLaughlin, Paul Demers, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Susan Peters, Roel Vermeulen, Hans Kromhout, Thomas Brüning, Ann C Olsson. 1. The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (Drs Bigert, Gustavsson); International Agency for Research on Cancer, Lyon, France (Drs Straif, Schüz, Olsson); Institute for Prevention and Occupational Medicine of the German Social Accident Insurance - Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany (Drs Taeger, Pesch, Kendzia, Brüning); Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Environmental Epidemiology of Cancer Team (Drs Stücker, Guida); Université Paris-Sud, UMRS 1018, F-94807, Villejuif, France (Drs Stücker, Guida); Institut für Epidemiologie I, Deutsches Forschungszentrum für Gesundheit und Umwelt, Neuherberg (Dr Brüske); Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians University (Dr Wichmann); Helmholtz Center Munich, Institute of Epidemiology I (Dr Wichmann); Institute of Medical Statistics and Epidemiology, Technical University Munich, Munich, Germany (Dr Wichmann); Department of Clinical Sciences and Community Health, Università degli Studi di Milano and IRCCS Ca' Granda Foundation, Milan, Italy (Dr Pesatori); National Cancer Institute, Bethesda, Maryland (Drs Landi, Caporaso); Division of Occupational and Environmental Health, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China (Drs Tse, Yu); Research Centre of University of Montréal Hospital Centre, University of Montréal, Montréal, Quebec, Canada (Drs Siemiatycki, Lavoué); Cancer Epidemiology Unit, Department of Medical Sciences, University of Turin, Turin, Italy (Drs Richiardi, Mirabelli); Department of Environmental Medicine and Public Health, University of Padua, Padua, Italy (Dr Simonato); Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany (Dr Jöckel); Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany (Drs Ahrens, Pohlabeln); CIBERESP, University of Oviedo, Oviedo, Spain (Dr Tardón); Russian Cancer Research Centre, Moscow, Russia (Dr Zaridze); Roy Castle Lung Cancer Research Programme, Cancer Research Centre, University of Liverpool, Liverpool, UK (Dr Field); Centre for Public Health Research, Massey University, Wellington, New Zealand (Drs 't Mannetje, Pearce); Public Health Ontario, Toronto (Dr McLaughlin); Occupational Cancer Research Centre, Cancer Care Ontario, Ontario, Toronto, Canada (Dr Demers); The Nofer Institute of Occupational Medicine, Lodz (Dr Szeszenia-Dabrowska); The M Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland (Dr Lissowska); National Public Health Center, Budapest, Hungary (Dr Rudnai); Regional Authority of Public Health, Banska Bystrica, Slovakia (Dr Fabianova); Institute of Public Health, Bucharest, Romania (Dr Stanescu Dumitru); Institute of Hygiene and Epidemiology, 1st Faculty of Medicine, Charles University, Prague (Dr Bencko); Masaryk Memorial Cancer Institute, Brno, Czech Republic (Dr Foretova); Palacky University, Faculty of Medicine, Olomouc (Dr Janout); Faculty of Medicine, Ostrava University, Ostrava, Czech Republic (Dr Janout); The Tisch Cancer Institute and Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, New York (Dr Boffetta); Institute for Risk Assessment Sciences, Utrecht, the Netherlands (Drs Peters, Vermeulen, Kromhout); and Occupational Respiratory Epidemiology, School of Population Health, University of Western Australia, Perth, Western Australia, Australia (Dr Peters).
Abstract
OBJECTIVES: The aim of this study was to explore lung cancer risk among firefighters, with adjustment for smoking. METHODS: We used pooled information from the SYNERGY project including 14 case-control studies conducted in Europe, Canada, New Zealand, and China, with lifetime work histories and smoking habits for 14,748 cases of lung cancer and 17,543 controls. We estimated odds ratios by unconditional logistic regression with adjustment for smoking and having ever been employed in a job known to present an excess risk of lung cancer. RESULTS: There was no increased lung cancer risk overall or by specific cell type among firefighters (n = 190), neither before nor after smoking adjustment. We observed no significant exposure-response relationship in terms of work duration. CONCLUSIONS: We found no evidence of an excess lung cancer risk related to occupational exposure as a firefighter.
OBJECTIVES: The aim of this study was to explore lung cancer risk among firefighters, with adjustment for smoking. METHODS: We used pooled information from the SYNERGY project including 14 case-control studies conducted in Europe, Canada, New Zealand, and China, with lifetime work histories and smoking habits for 14,748 cases of lung cancer and 17,543 controls. We estimated odds ratios by unconditional logistic regression with adjustment for smoking and having ever been employed in a job known to present an excess risk of lung cancer. RESULTS: There was no increased lung cancer risk overall or by specific cell type among firefighters (n = 190), neither before nor after smoking adjustment. We observed no significant exposure-response relationship in terms of work duration. CONCLUSIONS: We found no evidence of an excess lung cancer risk related to occupational exposure as a firefighter.
Authors: Ghislaine Scélo; Vali Constantinescu; Irma Csiki; David Zaridze; Neonila Szeszenia-Dabrowska; Peter Rudnai; Jolanta Lissowska; Eleonóra Fabiánová; Adrian Cassidy; Alena Slamova; Lenka Foretova; Vladimir Janout; Joelle Fevotte; Tony Fletcher; Andrea 't Mannetje; Paul Brennan; Paolo Boffetta Journal: Cancer Causes Control Date: 2004-06 Impact factor: 2.506
Authors: Ann C Olsson; Per Gustavsson; Hans Kromhout; Susan Peters; Roel Vermeulen; Irene Brüske; Beate Pesch; Jack Siemiatycki; Javier Pintos; Thomas Brüning; Adrian Cassidy; Heinz-Erich Wichmann; Dario Consonni; Maria Teresa Landi; Neil Caporaso; Nils Plato; Franco Merletti; Dario Mirabelli; Lorenzo Richiardi; Karl-Heinz Jöckel; Wolfgang Ahrens; Hermann Pohlabeln; Jolanta Lissowska; Neonila Szeszenia-Dabrowska; David Zaridze; Isabelle Stücker; Simone Benhamou; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Peter Rudnai; Eleonora Fabianova; Rodica Stanescu Dumitru; Isabelle M Gross; Benjamin Kendzia; Francesco Forastiere; Bas Bueno-de-Mesquita; Paul Brennan; Paolo Boffetta; Kurt Straif Journal: Am J Respir Crit Care Med Date: 2010-10-29 Impact factor: 21.405
Authors: Beate Pesch; Benjamin Kendzia; Per Gustavsson; Karl-Heinz Jöckel; Georg Johnen; Hermann Pohlabeln; Ann Olsson; Wolfgang Ahrens; Isabelle Mercedes Gross; Irene Brüske; Heinz-Erich Wichmann; Franco Merletti; Lorenzo Richiardi; Lorenzo Simonato; Cristina Fortes; Jack Siemiatycki; Marie-Elise Parent; Dario Consonni; Maria Teresa Landi; Neil Caporaso; David Zaridze; Adrian Cassidy; Neonila Szeszenia-Dabrowska; Peter Rudnai; Jolanta Lissowska; Isabelle Stücker; Eleonora Fabianova; Rodica Stanescu Dumitru; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Charles M Rudin; Paul Brennan; Paolo Boffetta; Kurt Straif; Thomas Brüning Journal: Int J Cancer Date: 2011-12-14 Impact factor: 7.396
Authors: Carolina Bigert; Per Gustavsson; Kurt Straif; Beate Pesch; Thomas Brüning; Benjamin Kendzia; Joachim Schüz; Isabelle Stücker; Florence Guida; Irene Brüske; Heinz-Erich Wichmann; Angela C Pesatori; Maria Teresa Landi; Neil Caporaso; Lap Ah Tse; Ignatius Tak-sun Yu; Jack Siemiatycki; Javier Pintos; Franco Merletti; Dario Mirabelli; Lorenzo Simonato; Karl-Heinz Jöckel; Wolfgang Ahrens; Hermann Pohlabeln; Adonina Tardón; David Zaridze; John Field; Andrea 't Mannetje; Neil Pearce; John McLaughlin; Paul Demers; Neonila Szeszenia-Dabrowska; Jolanta Lissowska; Peter Rudnai; Eleonora Fabianova; Rodica Stanescu Dumitru; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Paolo Boffetta; Francesco Forastiere; Bas Bueno-de-Mesquita; Susan Peters; Roel Vermeulen; Hans Kromhout; Ann C Olsson Journal: J Occup Environ Med Date: 2015-02 Impact factor: 2.162