Literature DB >> 27816488

At the crossroads of cancer stem cells and targeted therapy resistance.

Anbang Wang1, Le Qu2, Linhui Wang3.   

Abstract

Small-molecule targeted therapy (TT) has brought great hopes to patients with advanced malignancies. However, most patients suffer from tumor progression and relapse due to drug resistance. Recently, considerable efforts trying to elucidate the underlying mechanisms have focused on the contribution of cancer stem cells (CSCs) to the targeted therapy resistance (TTR). In this article, we provide an overview of the currently available literature on the rising roles of CSCs in TTR, as well as therapeutic opportunities of combining TT and anti-CSC therapy in the treatment of advanced malignancies. Copyright Â
© 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Anti-CSC therapy; Cancer stem cells; Combinational therapy; Targeted therapy; Targeted therapy resistance

Mesh：

Substances：

Year:  2016        PMID： 27816488     DOI： 10.1016/j.canlet.2016.10.039

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  11 in total

1.  Chrysin and Docetaxel Loaded Biodegradable Micelle for Combination Chemotherapy of Cancer Stem Cell.

Authors:  Aliyeh Ghamkhari; Ayda Pouyafar; Roya Salehi; Reza Rahbarghazi
Journal:  Pharm Res       Date:  2019-10-23       Impact factor: 4.200

Review 2.  Intratumor heterogeneity, microenvironment, and mechanisms of drug resistance in glioma recurrence and evolution.

Authors:  Zhaoshi Bao; Yongzhi Wang; Qiangwei Wang; Shengyu Fang; Xia Shan; Jiguang Wang; Tao Jiang
Journal:  Front Med       Date:  2021-04-24       Impact factor: 4.592

3.  Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer.

Authors:  Dominika E Butler; Christopher Marlein; Hannah F Walker; Fiona M Frame; Vincent M Mann; Matthew S Simms; Barry R Davies; Anne T Collins; Norman J Maitland
Journal:  Oncotarget       Date:  2017-05-23

4.  Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influx.

Authors:  Hugo Jimenez; Minghui Wang; Jacquelyn W Zimmerman; Michael J Pennison; Sambad Sharma; Trevor Surratt; Zhi-Xiang Xu; Ivan Brezovich; Devin Absher; Richard M Myers; Barry DeYoung; David L Caudell; Dongquan Chen; Hui-Wen Lo; Hui-Kuan Lin; Dwayne W Godwin; Michael Olivier; Anand Ghanekar; Kui Chen; Lance D Miller; Yijian Gong; Myles Capstick; Ralph B D'Agostino; Reginald Munden; Philippe Merle; Alexandre Barbault; Arthur W Blackstock; Herbert L Bonkovsky; Guang-Yu Yang; Guangxu Jin; Liang Liu; Wei Zhang; Kounosuke Watabe; Carl F Blackman; Boris C Pasche
Journal:  EBioMedicine       Date:  2019-05-31       Impact factor: 8.143

Review 5.  Concise Reviews: Cancer Stem Cell Targeted Therapies: Toward Clinical Success.

Authors:  Amar Desai; Yan Yan; Stanton L Gerson
Journal:  Stem Cells Transl Med       Date:  2018-10-17       Impact factor: 6.940

6.  Gold quantum dots impair the tumorigenic potential of glioma stem-like cells via β-catenin downregulation in vitro.

Authors:  Rizwan Wahab; Neha Kaushik; Farheen Khan; Nagendra Kumar Kaushik; Su-Jae Lee; Eun Ha Choi; Abdulaziz A Al-Khedhairy
Journal:  Int J Nanomedicine       Date:  2019-02-13

Review 7.  The Breast Cancer Stem Cells Traits and Drug Resistance.

Authors:  Qinghui Zheng; Mengdi Zhang; Fangfang Zhou; Long Zhang; Xuli Meng
Journal:  Front Pharmacol       Date:  2021-01-28       Impact factor: 5.810

8.  Exploring novel capping framework: high substituent pyridine-hydroxamic acid derivatives as potential antiproliferative agents.

Authors:  Fernando Hernández-Borja; Itzel Mercado-Sánchez; Yolanda Alcaraz; Marco A García-Revilla; Clarisa Villegas Gómez; David Ordaz-Rosado; Nancy Santos-Martínez; Rocío García-Becerra; Miguel A Vazquez
Journal:  Daru       Date:  2021-07-23       Impact factor: 4.088

Review 9.  Cancer stem cells and strategies for targeted drug delivery.

Authors:  Jin Cao; Shubhmita Bhatnagar; Jiawei Wang; Xueyong Qi; Swayam Prabha; Jayanth Panyam
Journal:  Drug Deliv Transl Res       Date:  2020-10-23       Impact factor: 5.671

Review 10.  Cripto-1 as a Potential Target of Cancer Stem Cells for Immunotherapy.

Authors:  Hiroko Ishii; Said M Afify; Ghmkin Hassan; David S Salomon; Masaharu Seno
Journal:  Cancers (Basel)       Date:  2021-05-20       Impact factor: 6.639
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