Boel Johnsen1, Kristine Eldevik Fasmer2, Kjetil Boye3, Karen Rosendahl4,5, Clement Trovik5,6, Martin Biermann7,5, Stein Magnus Aukland4,5. 1. Centre for Nuclear Medicine and PET, Department of Radiology, Haukeland University Hospital, P.O. Box 1400, 5021, Bergen, Norway. boel.johnsen@helse-bergen.no. 2. Department of Oncology, Medical Physics Section, Haukeland University Hospital, Bergen, Norway. 3. Department of Oncology, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway. 4. Department of Radiology, Paediatric Section, Haukeland University Hospital, Bergen, Norway. 5. Department of Clinical Medicine, University of Bergen, Bergen, Norway. 6. Department of Surgery, Orthopaedic Section, Haukeland University Hospital, Bergen, Norway. 7. Centre for Nuclear Medicine and PET, Department of Radiology, Haukeland University Hospital, P.O. Box 1400, 5021, Bergen, Norway.
Abstract
BACKGROUND: Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. OBJECTIVE: To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether 18F-fluorodeoxyglucose positron emission tomography - computed tomography (18F-FDG PET-CT) is a major contributor of radiation. MATERIALS AND METHODS: Twenty Ewing sarcoma patients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. RESULTS: The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). CONCLUSION: There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT.
BACKGROUND:Patients with Ewing sarcoma are subject to various diagnostic procedures that incur exposure to ionising radiation. OBJECTIVE: To estimate the radiation doses received from all radiologic and nuclear imaging episodes during diagnosis and treatment, and to determine whether 18F-fluorodeoxyglucose positron emission tomography - computed tomography (18F-FDG PET-CT) is a major contributor of radiation. MATERIALS AND METHODS: Twenty Ewing sarcomapatients diagnosed in Norway in 2005-2012 met the inclusion criteria (age <30 years, operable disease, uncomplicated chemotherapy and surgery, no metastasis or residual disease within a year of diagnosis). Radiation doses from all imaging during the first year were calculated for each patient. RESULTS: The mean estimated cumulative radiation dose for all patients was 34 mSv (range: 6-70), radiography accounting for 3 mSv (range: 0.2-12), CT for 13 mSv (range: 2-28) and nuclear medicine for 18 mSv (range: 2-47). For the patients examined with PET-CT, the mean estimated cumulative effective dose was 38 mSv, of which PET-CT accounted for 14 mSv (37%). CONCLUSION: There was large variation in number and type of examinations performed and also in estimated cumulative radiation dose. The mean radiation dose for patients examined with PET-CT was 23% higher than for patients not examined with PET-CT.
Authors: Michael J Gelfand; Susan E Sharp; S Ted Treves; Frederic H Fahey; Marguerite T Parisi; Adam M Alessio Journal: Pediatr Radiol Date: 2010-08-13
Authors: L Krille; S Dreger; R Schindel; T Albrecht; M Asmussen; J Barkhausen; J D Berthold; A Chavan; C Claussen; M Forsting; E A L Gianicolo; K Jablonka; A Jahnen; M Langer; M Laniado; J Lotz; H J Mentzel; A Queißer-Wahrendorf; O Rompel; I Schlick; K Schneider; M Schumacher; M Seidenbusch; C Spix; B Spors; G Staatz; T Vogl; J Wagner; G Weisser; H Zeeb; M Blettner Journal: Radiat Environ Biophys Date: 2015-01-08 Impact factor: 1.925