Literature DB >> 27814478

Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value.

Atilgan Yilmaz1, Mordecai Peretz1, Ido Sagi2, Nissim Benvenisty3.   

Abstract

Recent advances in the generation of haploid embryonic stem cells (ESCs), capable of self-renewal and differentiation, have laid the groundwork for numerous biomedical applications in developmental biology and reproductive medicine. When combined with the power of genetic screening, haploid human ESCs could advance cancer research, regenerative medicine, and disease modeling.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27814478     DOI： 10.1016/j.stem.2016.10.009

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  11 in total

1.  Stabilization of mouse haploid embryonic stem cells with combined kinase and signal modulation.

Authors:  Haisen Li; Ao Guo; Zhenfei Xie; Wanzhi Tu; Jiali Yu; Huihan Wang; Jian Zhao; Cuiqing Zhong; Jiuhong Kang; Jinsong Li; Shichao Huang; Li Shen
Journal:  Sci Rep       Date:  2017-10-16       Impact factor: 4.379

2.  Haploid embryonic stem cells can be enriched and maintained by simple filtration.

Authors:  Chao Qu; Meng Yan; Suming Yang; Lingbo Wang; Qi Yin; Yuan Liu; Yeguang Chen; Jinsong Li
Journal:  J Biol Chem       Date:  2018-02-15       Impact factor: 5.157

3.  A p53-dependent response limits the viability of mammalian haploid cells.

Authors:  Teresa Olbrich; Cristina Mayor-Ruiz; Maria Vega-Sendino; Carmen Gomez; Sagrario Ortega; Sergio Ruiz; Oscar Fernandez-Capetillo
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-14       Impact factor: 11.205

4.  Arrayed mutant haploid embryonic stem cell libraries facilitate phenotype-driven genetic screens.

Authors:  Guang Liu; Xue Wang; Yufang Liu; Meili Zhang; Tao Cai; Zhirong Shen; Yuyan Jia; Yue Huang
Journal:  Nucleic Acids Res       Date:  2017-12-15       Impact factor: 16.971

5.  A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells.

Authors:  Teresa Olbrich; Maria Vega-Sendino; Matilde Murga; Guillermo de Carcer; Marcos Malumbres; Sagrario Ortega; Sergio Ruiz; Oscar Fernandez-Capetillo
Journal:  Cell Rep       Date:  2019-07-16       Impact factor: 9.423

Review 6.  Current advances in haploid stem cells.

Authors:  Tongtong Cui; Zhikun Li; Qi Zhou; Wei Li
Journal:  Protein Cell       Date:  2019-04-19       Impact factor: 14.870

7.  Efficient and crucial quality control of HAP1 cell ploidy status.

Authors:  Tobias B Beigl; Ine Kjosås; Emilie Seljeseth; Nina Glomnes; Henriette Aksnes
Journal:  Biol Open       Date:  2020-11-12       Impact factor: 2.422

8.  A Genetic Screen Identifies Etl4-Deficiency Capable of Stabilizing the Haploidy in Embryonic Stem Cells.

Authors:  Guozhong Zhang; Xiaowen Li; Yi Sun; Xue Wang; Guang Liu; Yue Huang
Journal:  Stem Cell Reports       Date:  2021-01-12       Impact factor: 7.765

9.  Delayed DNA replication in haploid human embryonic stem cells.

Authors:  Matthew M Edwards; Michael V Zuccaro; Ido Sagi; Qiliang Ding; Dan Vershkov; Nissim Benvenisty; Dieter Egli; Amnon Koren
Journal:  Genome Res       Date:  2021-11-22       Impact factor: 9.438

Review 10.  A versatile genetic tool: haploid cells.

Authors:  Yanni Li; Ling Shuai
Journal:  Stem Cell Res Ther       Date:  2017-09-29       Impact factor: 6.832
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