Literature DB >> 27813216

Recent Progress Toward the Synthesis of Trifluoromethyl- and Difluoromethyl-Substituted Cyclopropanes.

Maxence Bos1, Thomas Poisson1, Xavier Pannecoucke1, André B Charette2, Philippe Jubault1.   

Abstract

This Minireview describes recent advances toward the synthesis of trifluoromethyl- and difluoromethyl-substituted cyclopropanes. Synthetic methodologies using [2+1] cycloaddition, ring-contraction, and ring-closure cyclopropanations since 2010 are reported.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  difluoromethyl; fluorine; substituted cyclopropanes; synthetic methods; trifluoromethyl

Year:  2017        PMID： 27813216     DOI： 10.1002/chem.201604564

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  4 in total

1.  Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene.

Authors:  Antonio Tinoco; Viktoria Steck; Vikas Tyagi; Rudi Fasan
Journal:  J Am Chem Soc       Date:  2017-04-10       Impact factor: 15.419

2.  Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2 -Containing Trisubstituted Cyclopropanes.

Authors:  Daniela M Carminati; Jonathan Decaens; Samuel Couve-Bonnaire; Philippe Jubault; Rudi Fasan
Journal:  Angew Chem Int Ed Engl       Date:  2021-02-17       Impact factor: 15.336

3.  Use of trifluoroacetaldehyde N-tfsylhydrazone as a trifluorodiazoethane surrogate and its synthetic applications.

Authors:  Xinyu Zhang; Zhaohong Liu; Xiangyu Yang; Yuanqing Dong; Matteo Virelli; Giuseppe Zanoni; Edward A Anderson; Xihe Bi
Journal:  Nat Commun       Date:  2019-01-17       Impact factor: 14.919

4.  Electrogenerated base-promoted cyclopropanation using alkyl 2-chloroacetates.

Authors:  Kouichi Matsumoto; Yuta Hayashi; Kengo Hamasaki; Mizuki Matsuse; Hiyono Suzuki; Keiji Nishiwaki; Norihito Kawashita
Journal:  Beilstein J Org Chem       Date:  2022-08-29       Impact factor: 2.544
  4 in total

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