Literature DB >> 27813172

Digitization of Endocytic pH by Hybrid Ultra-pH-Sensitive Nanoprobes at Single-Organelle Resolution.

Yiguang Wang1,2, Chensu Wang1,3, Yang Li1, Gang Huang1, Tian Zhao1, Xinpeng Ma1, Zhaohui Wang1, Baran D Sumer4, Michael A White3, Jinming Gao1.   

Abstract

A multispectral hybrid nanotransistor consisting of modular fluorescent block copolymers with discrete and sharp pH transitions in one nanoparticluate system is presented. This nanotransistor probe allows digitized reporting of dynamic maturation at single-organelle resolution over time. This nanotechnology platform offers a powerful tool in fundamental studies of organelle biology, cell signaling in diseases characterized by pH dysregulation in the endosomes or lysosomes.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  acidification; endocytosis; hybrid nanoprobes; organelle maturation; pH-sensitive nanoparticles

Year:  2016        PMID： 27813172     DOI： 10.1002/adma.201603794

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  14 in total

Review 1.  Cooperativity Principles in Self-Assembled Nanomedicine.

Authors:  Yang Li; Yiguang Wang; Gang Huang; Jinming Gao
Journal:  Chem Rev       Date:  2018-04-25       Impact factor: 60.622

Review 2.  Transistor-like Ultra-pH-Sensitive Polymeric Nanoparticles.

Authors:  Qiang Feng; Jonathan Wilhelm; Jinming Gao
Journal:  Acc Chem Res       Date:  2019-05-08       Impact factor: 22.384

Review 3.  Polyvalent design in the cGAS-STING pathway.

Authors:  Zachary T Bennett; Suxin Li; Baran D Sumer; Jinming Gao
Journal:  Semin Immunol       Date:  2021-12-15       Impact factor: 11.130

4.  Distinct ON/OFF fluorescence signals from dual-responsive activatable nanoprobes allows detection of inflammation with improved contrast.

Authors:  Mathieu L Viger; Guillaume Collet; Jacques Lux; Viet Anh Nguyen Huu; Monica Guma; Alexandra Foucault-Collet; Jason Olejniczak; Shivanjali Joshi-Barr; Gary S Firestein; Adah Almutairi
Journal:  Biomaterials       Date:  2017-03-28       Impact factor: 12.479

5.  Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles.

Authors:  Suxin Li; Zachary T Bennett; Baran D Sumer; Jinming Gao
Journal:  Acc Chem Res       Date:  2020-10-16       Impact factor: 22.384

6.  Ultrasensitive (Co)polymers Based on Poly(methacrylamide) Structure with Fining-Tunable pH Responsive Value.

Authors:  Haiming Fan; Po Li; Wei Li; Hui Li; Xiaonan Huang
Journal:  Molecules       Date:  2018-07-27       Impact factor: 4.411

Review 7.  Smart Nanomaterials for Biomedical Applications-A Review.

Authors:  Magdalena Aflori
Journal:  Nanomaterials (Basel)       Date:  2021-02-04       Impact factor: 5.076

Review 8.  Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.

Authors:  Wei Wu; Li Luo; Yi Wang; Qi Wu; Han-Bin Dai; Jian-Shu Li; Colm Durkan; Nan Wang; Gui-Xue Wang
Journal:  Theranostics       Date:  2018-04-30       Impact factor: 11.556

Review 9.  Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics.

Authors:  Peng Mi
Journal:  Theranostics       Date:  2020-03-15       Impact factor: 11.556

10.  Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.

Authors:  Amy H Ponsford; Thomas A Ryan; Andrea Raimondi; Emanuele Cocucci; Susanne A Wycislo; Florian Fröhlich; Laura E Swan; Massimiliano Stagi
Journal:  Autophagy       Date:  2020-06-09       Impact factor: 16.016
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.