Literature DB >> 27812933

Primer on the Gene Ontology.

Pascale Gaudet1,2, Nives Škunca3,4,5, James C Hu6, Christophe Dessimoz7,8,9,10,11.   

Abstract

The Gene Ontology (GO) project is the largest resource for cataloguing gene function. The combination of solid conceptual underpinnings and a practical set of features have made the GO a widely adopted resource in the research community and an essential resource for data analysis. In this chapter, we provide a concise primer for all users of the GO. We briefly introduce the structure of the ontology and explain how to interpret annotations associated with the GO.

Entities:  

Keywords:  Annotation evidence; Annotations; Evidence codes; Function; GO files; Gene Ontology structure; Gene association file (GAF); Vocabulary

Mesh:

Substances:

Year:  2017        PMID: 27812933      PMCID: PMC6377150          DOI: 10.1007/978-1-4939-3743-1_3

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  20 in total

1.  CDK1-PLK1/SGOL2/ANLN pathway mediating abnormal cell division in cell cycle may be a critical process in hepatocellular carcinoma.

Authors:  Ling Li; Kang Huang; Huijia Zhao; Binyao Chen; Qifa Ye; Jiang Yue
Journal:  Cell Cycle       Date:  2020-04-10       Impact factor: 4.534

2.  Using Drosophila melanogaster To Discover Human Disease Genes: An Educational Primer for Use with "Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target".

Authors:  Surya Banerjee; Shimshon Benji; Sarah Liberow; Josefa Steinhauer
Journal:  Genetics       Date:  2020-11       Impact factor: 4.562

3.  VWCE as a potential biomarker associated with immune infiltrates in breast cancer.

Authors:  Qin Huo; Zhenwei Li; Siqi Chen; Juan Wang; Jiaying Li; Ni Xie
Journal:  Cancer Cell Int       Date:  2021-05-21       Impact factor: 5.722

4.  Identification of Key Genes and miRNAs in Osteosarcoma Patients with Chemoresistance by Bioinformatics Analysis.

Authors:  Binbin Xie; Yiran Li; Rongjie Zhao; Yuzi Xu; Yuhui Wu; Ji Wang; Dongdong Xia; Weidong Han; Dake Chen
Journal:  Biomed Res Int       Date:  2018-04-22       Impact factor: 3.411

5.  The Identification of Core Gene Expression Signature in Hepatocellular Carcinoma.

Authors:  Ning Li; Ling Li; Yongshun Chen
Journal:  Oxid Med Cell Longev       Date:  2018-05-27       Impact factor: 6.543

6.  Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

Authors:  Valerie Wood; Antonia Lock; Midori A Harris; Kim Rutherford; Jürg Bähler; Stephen G Oliver
Journal:  Open Biol       Date:  2019-02-28       Impact factor: 6.411

7.  Annotation of gene product function from high-throughput studies using the Gene Ontology.

Authors:  Helen Attrill; Pascale Gaudet; Rachael P Huntley; Ruth C Lovering; Stacia R Engel; Sylvain Poux; Kimberly M Van Auken; George Georghiou; Marcus C Chibucos; Tanya Z Berardini; Valerie Wood; Harold Drabkin; Petra Fey; Penelope Garmiri; Midori A Harris; Tony Sawford; Leonore Reiser; Rebecca Tauber; Sabrina Toro
Journal:  Database (Oxford)       Date:  2019-01-01       Impact factor: 3.451

8.  Bioinformatics analysis reveals meaningful markers and outcome predictors in HBV-associated hepatocellular carcinoma.

Authors:  Lijie Zhang; Joyman Makamure; Dan Zhao; Yiming Liu; Xiaopeng Guo; Chuansheng Zheng; Bin Liang
Journal:  Exp Ther Med       Date:  2020-05-06       Impact factor: 2.447

9.  From Affective Science to Psychiatric Disorder: Ontology as a Semantic Bridge.

Authors:  Rasmus Rosenberg Larsen; Janna Hastings
Journal:  Front Psychiatry       Date:  2018-10-08       Impact factor: 4.157

10.  The Gene Ontology Resource: 20 years and still GOing strong.

Authors: 
Journal:  Nucleic Acids Res       Date:  2019-01-08       Impact factor: 16.971

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