Literature DB >> 27811270

Exploring pain pathophysiology in patients.

Claudia Sommer1.   

Abstract

Although animal models of pain have brought invaluable information on basic processes underlying pain pathophysiology, translation to humans is a problem. This Review will summarize what information has been gained by the direct study of patients with chronic pain. The techniques discussed range from patient phenotyping using quantitative sensory testing to specialized nociceptor neurophysiology, imaging methods of peripheral nociceptors, analyses of body fluids, genetics and epigenetics, and the generation of sensory neurons from patients via inducible pluripotent stem cells.
Copyright © 2016, American Association for the Advancement of Science.

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Year:  2016        PMID： 27811270     DOI： 10.1126/science.aaf8935

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Soluble intercellular adhesion molecule-1: a potential biomarker for pain intensity in chronic pain patients.

Authors:  Benjamin Luchting; Ludwig Christian Giuseppe Hinske; Banafscheh Rachinger-Adam; Leo Anthony Celi; Simone Kreth; Shahnaz Christina Azad
Journal:  Biomark Med       Date:  2017-02-16       Impact factor: 2.851

2.  Digital Phenotyping in Clinical Neurology.

Authors:  Anoopum S Gupta
Journal:  Semin Neurol       Date:  2022-01-11       Impact factor: 3.212

Review 3.  From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain.

Authors:  Theodore J Price; Michael S Gold
Journal:  Pain Med       Date:  2018-08-01       Impact factor: 3.750

4.  Test-Retest and Inter-Examiner Reliability of a Novel Bedside Quantitative Sensory Testing Battery in Postherpetic Neuralgia Patients.

Authors:  Ajay D Wasan; Benedict J Alter; Robert R Edwards; Charles E Argoff; Nalini Sehgal; David Walk; Toby Moeller-Bertram; Mark S Wallace; Misha Backonja
Journal:  J Pain       Date:  2019-12-11       Impact factor: 5.820

Review 5.  Advances in understanding nociception and neuropathic pain.

Authors:  Ewan St John Smith
Journal:  J Neurol       Date:  2017-10-14       Impact factor: 4.849

6.  Sub-maximal endurance exercise does not mediate alterations of somatosensory thresholds.

Authors:  Ann-Christin Kortenjann; Winfried Banzer; Johannes Fleckenstein
Journal:  Sci Rep       Date:  2020-07-01       Impact factor: 4.379

Review 7.  Second edition of SIMPAR's "Feed Your Destiny" workshop: the role of lifestyle in improving pain management.

Authors:  Manuela De Gregori; Inna Belfer; Roberto De Giorgio; Maurizio Marchesini; Carolina Muscoli; Mariangela Rondanelli; Daniela Martini; Pedro Mena; Laura Isabel Arranz; Silvia Lorente-Cebrián; Simone Perna; Anna Villarini; Maurizio Salamone; Massimo Allegri; Michael E Schatman
Journal:  J Pain Res       Date:  2018-08-27       Impact factor: 3.133

8.  Region-Resolved Quantitative Proteome Profiling Reveals Molecular Dynamics Associated With Chronic Pain in the PNS and Spinal Cord.

Authors:  Allison M Barry; Julia R Sondermann; Jan-Hendrik Sondermann; David Gomez-Varela; Manuela Schmidt
Journal:  Front Mol Neurosci       Date:  2018-08-14       Impact factor: 5.639

Review 9.  The NaV1.7 Channel Subtype as an Antinociceptive Target for Spider Toxins in Adult Dorsal Root Ganglia Neurons.

Authors:  Tânia C Gonçalves; Evelyne Benoit; Michel Partiseti; Denis Servent
Journal:  Front Pharmacol       Date:  2018-09-04       Impact factor: 5.810

10.  Burst Spinal Cord Stimulation: A Clinical Review.

Authors:  Terje Kirketeig; Carsten Schultheis; Xander Zuidema; Corey W Hunter; Timothy Deer
Journal:  Pain Med       Date:  2019-06-01       Impact factor: 3.750
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