Literature DB >> 27810073

The emerging role of long non-coding RNAs in endometrial cancer.

Konii Takenaka1, Bei Jun Chen1, Susan C Modesitt2, Frances L Byrne1, Kyle L Hoehn1, Michael Janitz3.   

Abstract

The human genome is pervasively transcribed and approximately 98% of the genome is non-coding. Long non-coding RNAs (lncRNAs) are a heterogeneous group of RNA transcripts that are >200 nucleotides in length with minimal to no protein-coding potential. Similar to proteins, lncRNAs have important biological functions in both normal cells and disease states including many types of cancer. This review summarizes recent advances in our understanding of lncRNAs in cancer biology and highlights the potential for lncRNA as diagnostic biomarkers and therapeutics. Herein we focus on the poorly understood role of lncRNAs in endometrial cancer, the most common gynecologic malignancy in the developed world.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Endometrial cancer; gene expression; lincRNAs; long non-coding RNAs; transcriptome

Mesh：

Substances：

Year:  2016        PMID： 27810073     DOI： 10.1016/j.cancergen.2016.09.005

Source DB:  PubMed          Journal:  Cancer Genet


  17 in total

1.  STAT1-induced upregulation of lncRNA LINC01123 predicts poor prognosis and promotes the progression of endometrial cancer through miR-516b/KIF4A.

Authors:  Yuguang Yang; Jin Wu; Hongfeng Zhou; Wenming Liu; Jincai Wang; Qingyuan Zhang
Journal:  Cell Cycle       Date:  2020-05-13       Impact factor: 4.534

Review 2.  LncRNA-miRNA-mRNA regulatory axes in endometrial cancer: a comprehensive overview.

Authors:  Abhishek Shetty; Thejaswini Venkatesh; Shama Prasada Kabbekodu; Rie Tsutsumi; Padmanaban S Suresh
Journal:  Arch Gynecol Obstet       Date:  2022-02-18       Impact factor: 2.493

Review 3.  Long non-coding RNAs in hepatocellular carcinoma: Potential roles and clinical implications.

Authors:  Zhao-Shan Niu; Xiao-Jun Niu; Wen-Hong Wang
Journal:  World J Gastroenterol       Date:  2017-08-28       Impact factor: 5.742

4.  Prognostic value of long noncoding RNA ZFAS1 in various carcinomas: a meta-analysis.

Authors:  Dan Dong; Zhongyi Mu; Wei Wang; Na Xin; Xiaowen Song; Yue Shao; Chenghai Zhao
Journal:  Oncotarget       Date:  2017-09-20

5.  LINC00565 Enhances Proliferative Ability in Endometrial Carcinoma by Downregulating KLF9.

Authors:  Xiuyan Yin; Xiaohong Li; Guijiao Feng; Yuejie Qu; Hong Wang
Journal:  Onco Targets Ther       Date:  2020-06-29       Impact factor: 4.147

6.  Identification of mRNAs related to endometrium function regulated by lncRNA CD36-005 in rat endometrial stromal cells.

Authors:  Xueying Zhang; Ying Xu; Lulu Fu; Dandan Li; Xiaowei Dai; Lianlian Liu; Jingshun Zhang; Lianwen Zheng; Manhua Cui
Journal:  Reprod Biol Endocrinol       Date:  2018-10-15       Impact factor: 5.211

Review 7.  The Emerging Role of Major Regulatory RNAs in Cancer Control.

Authors:  Xiaofeng Dai; Aman Chandra Kaushik; Jianying Zhang
Journal:  Front Oncol       Date:  2019-09-24       Impact factor: 6.244

8.  Long noncoding RNA LSINCT5 promotes endometrial carcinoma cell proliferation, cycle, and invasion by promoting the Wnt/β-catenin signaling pathway via HMGA2.

Authors:  Hongye Jiang; Yong Li; Jie Li; Xuyu Zhang; Gang Niu; Shuqin Chen; Shuzhong Yao
Journal:  Ther Adv Med Oncol       Date:  2019-09-29       Impact factor: 8.168

Review 9.  Emerging role of long non-coding RNA in the development of gastric cancer.

Authors:  Hang Yu; Long Rong
Journal:  World J Gastrointest Oncol       Date:  2018-09-15

Review 10.  Proteomic Biomarkers for the Detection of Endometrial Cancer.

Authors:  Kelechi Njoku; Davide Chiasserini; Anthony D Whetton; Emma J Crosbie
Journal:  Cancers (Basel)       Date:  2019-10-16       Impact factor: 6.639
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