Literature DB >> 27809596

An overview on different strategies for the stemness maintenance of MSCs.

Khatereh Saei Arezoumand1,2, Effat Alizadeh1,2, Younes Pilehvar-Soltanahmadi1,2, Mohammad Esmaeillou3, Nosratollah Zarghami1,2.   

Abstract

Recent evidence suggests that mesenchymal stem cells (MSCs) have promising therapeutic potential for a broad range of diseases. Because the percentage of MSCs obtained from tissues is very low for cell therapy applications, ex vivo expansion of MSCs is necessary, but aging, loss of stemness and undesired differentiation of them during in vitro cultivation reduces their effectiveness. For achieving ideal therapeutic potential of MSCs in tissue regenerative purposes, it is necessary to retain their stemness properties in vitro. This review emphasis on the last updates in preserving the self-renewal capability of stem cells through in vitro expansion with different parameters.

Entities:  

Keywords:  MSCs; Stemness; differentiation; regenerative medicine

Mesh：

Substances：

Year:  2016        PMID： 27809596     DOI： 10.1080/21691401.2016.1246452

Source DB:  PubMed          Journal:  Artif Cells Nanomed Biotechnol        ISSN： 2169-1401            Impact factor:   5.678


  10 in total

1.  Isolation, culture, and characterization of chicken lung-derived mesenchymal stem cells.

Authors:  Xishuai Wang; F H C; J J Wang; Hongda Ji; Weijun Guan; Yuhua Zhao
Journal:  Can J Vet Res       Date:  2018-07       Impact factor: 1.310

2.  The emu oil emulsified in egg lecithin and butylated hydroxytoluene enhanced the proliferation, stemness gene expression, and in vitro wound healing of adipose-derived stem cells.

Authors:  Khatereh Saei Arezoumand; Effat Alizadeh; Mohammad Esmaeillou; Maryam Ghasemi; Shahriar Alipour; Younes Pilehvar-Soltanahmadi; Nosratollah Zarghami
Journal:  In Vitro Cell Dev Biol Anim       Date:  2018-01-29       Impact factor: 2.416

3.  Soft substrate maintains proliferative and adipogenic differentiation potential of human mesenchymal stem cells on long-term expansion by delaying senescence.

Authors:  Sanjay Kumar Kureel; Pankaj Mogha; Akshada Khadpekar; Vardhman Kumar; Rohit Joshi; Siddhartha Das; Jayesh Bellare; Abhijit Majumder
Journal:  Biol Open       Date:  2019-04-25       Impact factor: 2.422

4.  Characterization of Mesenchymal Stem Cell Differentiation within Miniaturized 3D Scaffolds through Advanced Microscopy Techniques.

Authors:  Valentina Parodi; Emanuela Jacchetti; Arianna Bresci; Benedetta Talone; Carlo M Valensise; Roberto Osellame; Giulio Cerullo; Dario Polli; Manuela T Raimondi
Journal:  Int J Mol Sci       Date:  2020-11-11       Impact factor: 5.923

5.  New Insight into Natural Extracellular Matrix: Genipin Cross-Linked Adipose-Derived Stem Cell Extracellular Matrix Gel for Tissue Engineering.

Authors:  Batzaya Nyambat; Yankuba B Manga; Chih-Hwa Chen; Uuganbayar Gankhuyag; Andi Pratomo Wp; Mantosh Kumar Satapathy; Er-Yuan Chuang
Journal:  Int J Mol Sci       Date:  2020-07-09       Impact factor: 5.923

Review 6.  Mitochondrial Transfer in Cardiovascular Disease: From Mechanisms to Therapeutic Implications.

Authors:  Jun Chen; Jinjie Zhong; Lin-Lin Wang; Ying-Ying Chen
Journal:  Front Cardiovasc Med       Date:  2021-11-26

7.  Peptide-Grafted Microspheres for Mesenchymal Stem Cell Sorting and Expansion by Selective Adhesion.

Authors:  Shuo Wu; Zongliang Wang; Yu Wang; Min Guo; Mengyang Zhou; Liqiang Wang; Jie Ma; Peibiao Zhang
Journal:  Front Bioeng Biotechnol       Date:  2022-04-12

8.  Stem cell microencapsulation maintains stemness in inflammatory microenvironment.

Authors:  Yajun Zhao; Yilin Shi; Huiqi Yang; Mengmeng Liu; Lanbo Shen; Shengben Zhang; Yue Liu; Jie Zhu; Jing Lan; Jianhua Li; Shaohua Ge
Journal:  Int J Oral Sci       Date:  2022-10-10       Impact factor: 24.897

Review 9.  Endogenous Repair and Regeneration of Injured Articular Cartilage: A Challenging but Promising Therapeutic Strategy.

Authors:  Hongzhi Hu; Weijian Liu; Caixia Sun; Qiuyuan Wang; Wenbo Yang; ZhiCai Zhang; Zhidao Xia; Zengwu Shao; Baichuan Wang
Journal:  Aging Dis       Date:  2021-06-01       Impact factor: 6.745

Review 10.  Mesenchymal and Induced Pluripotent Stem Cells-Derived Extracellular Vesicles: The New Frontier for Regenerative Medicine?

Authors:  Maria Magdalena Barreca; Patrizia Cancemi; Fabiana Geraci
Journal:  Cells       Date:  2020-05-08       Impact factor: 6.600
  10 in total

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