| Literature DB >> 27808287 |
Jie Li1, Linlin Zhang2, Yang Liu3, Jing Wen4, Di Wu1, Duo Xu1, Tatiana Segura1, Jing Jin5, Yunfeng Lu1, Hui Wang2.
Abstract
An efficient strategy for the intracellular delivery of proteins was developed based on assembling proteins with a self-crosslinkable polymer. Such a disulfide-crosslinking structure enhances the stability of the protein-polymer assembly, and also allows effective dissociation of the assembly in response to glutathione, which allows effective delivery of various proteins with high intracellular bioactivity.Entities:
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Year: 2016 PMID： 27808287 DOI： 10.1039/c6cc05099a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222