Literature DB >> 27808098

Corrigendum: Existence of G-quadruplex structures in promoter region of oncogenes confirmed by G-quadruplex DNA cross-linking strategy.

Libo Yuan, Tian Tian, Yuqi Chen, Shengyong Yan, Xiwen Xing, Zhengan Zhang, Qianqian Zhai, Liang Xu, Shaoru Wang, Xiaocheng Weng, Bifeng Yuan, Yuqi Feng, Xiang Zhou.   

Abstract

Entities:  

Year:  2016        PMID: 27808098      PMCID: PMC5141294          DOI: 10.1038/srep35896

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


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A recent study has reported that the structure of known compound 1 should be revised (revised compound 1, Fig. 1)1. We are aware that the structure of compound 1 reported in our Article is incorrect and should be revised. In addition, the structure of compound 1a should also be revised in the Article and Supplementary Information (Fig. 1). Revised compound 1a was the final product (HPLC purified) and was used in the pull-down experiments reported in the paper.
Figure 1

Revised structures.

The structure of compound 4 (Supplementary Information) should also be revised (Fig. 1). Revised Compound 4 was not used in any of the biological studies reported in our paper, and is an intermediate in the synthesis of revised compound 1a. These revised structures do not affect the central conclusions of the paper, because the biological active groups (bis-phenol) are unchanged.
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1.  Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.

Authors:  Paul E Reyes-Gutiérrez; Tomáš Kapal; Blanka Klepetářová; David Šaman; Radek Pohl; Zbigniew Zawada; Erika Kužmová; Miroslav Hájek; Filip Teplý
Journal:  Sci Rep       Date:  2016-03-23       Impact factor: 4.379

  1 in total

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