Dan Wang1, Yan Hong2, Li Zhu3, Xiaoli Wang4, Qin Lv5, Qin Zhou6, Miaohua Ruan1, Chao Chen3. 1. a Department of Neonatology , The First Affiliated Hospital of Wenzhou Medical University , Wenzhou , China. 2. b Taizhou Municipal Hospital , Taizhou , China. 3. c Children's Hospital of Fudan University , Shanghai , China. 4. d Shanghai Jiading Maternal and Child Care Hospital , Shanghai , China. 5. e Ningbo Women and Children's Hospital , Ningbo , China , and. 6. f Jiangsu Wuxi Maternal and Child Health Care Hospital , Wuxi , China.
Abstract
OBJECTIVE: To investigate the risk factors and outcomes of macrosomia in China. METHODS: This was a multicenter, retrospective cohort study conducted in China. 178 709 singletons weighing ≥ 2500 g with gestational ages of 37-44 weeks were included. We compared the macrosomia group (with birth weight (BW) ≥ 4000 g) with the nornosomic control group (weighting 2500-3999 g). RESULTS: The total prevalence of macrosomia was 8.70%. The strongest risk factors correlated with macrosomia were maternal obesity and gestational diabetes mellitus (GDM). The risks of obstetric and neonatal complications increased when infants had a BW of ≥4000 g. CONCLUSIONS: Obesity and GDM are the most prominent risk factors for macrosomia, and macrosomia is associated with adverse maternal and neonate outcomes. Therefore, monitoring and controlling maternal weight and blood glucose could decrease the prevalence of macrosomia or improve its poor outcomes.
OBJECTIVE: To investigate the risk factors and outcomes of macrosomia in China. METHODS: This was a multicenter, retrospective cohort study conducted in China. 178 709 singletons weighing ≥ 2500 g with gestational ages of 37-44 weeks were included. We compared the macrosomia group (with birth weight (BW) ≥ 4000 g) with the nornosomic control group (weighting 2500-3999 g). RESULTS: The total prevalence of macrosomia was 8.70%. The strongest risk factors correlated with macrosomia were maternal obesity and gestational diabetes mellitus (GDM). The risks of obstetric and neonatal complications increased when infants had a BW of ≥4000 g. CONCLUSIONS:Obesity and GDM are the most prominent risk factors for macrosomia, and macrosomia is associated with adverse maternal and neonate outcomes. Therefore, monitoring and controlling maternal weight and blood glucose could decrease the prevalence of macrosomia or improve its poor outcomes.
Authors: Irene Esteban-Cornejo; Pontus Henriksson; Cristina Cadenas-Sanchez; Jérémy Vanhelst; Maria Forsner; Frederic Gottrand; Mathilde Kersting; Luis A Moreno; Jonatan R Ruiz; Kurt Widhalm; Francisco B Ortega Journal: Matern Child Nutr Date: 2017-04-11 Impact factor: 3.092