Literature DB >> 2780567

Retinal transplant-mediated learning in a conditioned suppression task in rats.

P J Coffey1, R D Lund, J N Rawlins.   

Abstract

Retinae were transplanted from embryonic rats to a location over the midbrain of unilaterally anucleated newborn rats. At maturity, the rats were trained to "lever-press" for a food reward. By using a Pavlovian conditioned suppression paradigm, it was found that light delivered to the transplant could be recognized by the host rat as a conditioned stimulus, resulting in a reduced rate of lever pressing.

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Mesh:

Year:  1989        PMID: 2780567      PMCID: PMC298034          DOI: 10.1073/pnas.86.18.7248

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  3 in total

1.  Conditions for optic axon outgrowth.

Authors:  R D Lund; M H Hankin; A J Sefton; V H Perry
Journal:  Brain Behav Evol       Date:  1988       Impact factor: 1.808

2.  Retinal transplants can drive a pupillary reflex in host rat brains.

Authors:  H Klassen; R D Lund
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

3.  Specific projections of retina transplanted to rat brain.

Authors:  S C McLoon; R D Lund
Journal:  Exp Brain Res       Date:  1980       Impact factor: 1.972

  3 in total
  6 in total

1.  Associative plasticity in striatal transplants.

Authors:  P J Brasted; C Watts; T W Robbins; S B Dunnett
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

Review 2.  Neural regeneration and cell replacement: a view from the eye.

Authors:  Deepak Lamba; Mike Karl; Thomas Reh
Journal:  Cell Stem Cell       Date:  2008-06-05       Impact factor: 24.633

Review 3.  Behavioural consequences of neural transplantation.

Authors:  S B Dunnett
Journal:  J Neurol       Date:  1994-12       Impact factor: 4.849

4.  Ectopic eyes outside the head in Xenopus tadpoles provide sensory data for light-mediated learning.

Authors:  Douglas J Blackiston; Michael Levin
Journal:  J Exp Biol       Date:  2013-03-15       Impact factor: 3.312

5.  Restoration of the striatal circuitry: from developmental aspects toward clinical applications.

Authors:  Marie-Christin Pauly; Tobias Piroth; Máté Döbrössy; Guido Nikkhah
Journal:  Front Cell Neurosci       Date:  2012-04-19       Impact factor: 5.505

6.  Photoreceptor Differentiation following Transplantation of Allogeneic Retinal Progenitor Cells to the Dystrophic Rhodopsin Pro347Leu Transgenic Pig.

Authors:  H Klassen; J F Kiilgaard; K Warfvinge; M S Samuel; R S Prather; F Wong; R M Petters; M la Cour; M J Young
Journal:  Stem Cells Int       Date:  2012-04-09       Impact factor: 5.443

  6 in total

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