Literature DB >> 27805462

Cathepsin D as a therapeutic target in Alzheimer's disease.

Fabio Di Domenico1, Antonella Tramutola1, Marzia Perluigi1.   

Abstract

Entities:  

Keywords:  Alzheimer disease; Cathepsin D; autophagy; lysosomes; proteases

Mesh：

Substances：

Year:  2016        PMID： 27805462     DOI： 10.1080/14728222.2016.1252334

Source DB:  PubMed          Journal:  Expert Opin Ther Targets        ISSN： 1472-8222            Impact factor:   6.902


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  18 in total

1.  Targeting lysosome function causes selective cytotoxicity in VHL-inactivated renal cell carcinomas.

Authors:  Nadia Bouhamdani; Dominique Comeau; Alexandre Coholan; Kevin Cormier; Sandra Turcotte
Journal:  Carcinogenesis       Date:  2020-07-10       Impact factor: 4.944

Review 2.  mTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia.

Authors:  Fabio Di Domenico; Antonella Tramutola; Cesira Foppoli; Elizabeth Head; Marzia Perluigi; D Allan Butterfield
Journal:  Free Radic Biol Med       Date:  2017-08-12       Impact factor: 7.376

Review 3.  Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism.

Authors:  Eugenio Barone; Andrea Arena; Elizabeth Head; D Allan Butterfield; Marzia Perluigi
Journal:  Free Radic Biol Med       Date:  2017-07-10       Impact factor: 7.376

4.  Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure.

Authors:  Penglong Wu; Xun Yuan; Faqian Li; Jianhua Zhang; Wei Zhu; Meng Wei; Jingbo Li; Xuejun Wang
Journal:  Circ Heart Fail       Date:  2017-07-10       Impact factor: 8.790

Review 5.  Shared molecular and cellular mechanisms of premature ageing and ageing-associated diseases.

Authors:  Nard Kubben; Tom Misteli
Journal:  Nat Rev Mol Cell Biol       Date:  2017-08-09       Impact factor: 94.444

Review 6.  Extracellular Vesicles: Intercellular Mediators in Alcohol-Induced Pathologies.

Authors:  Mohammad A Rahman; Benjamin J Patters; Sunitha Kodidela; Santosh Kumar
Journal:  J Neuroimmune Pharmacol       Date:  2019-04-06       Impact factor: 4.147

7.  Exercise Rehabilitation and/or Astragaloside Attenuate Amyloid-beta Pathology by Reversing BDNF/TrkB Signaling Deficits and Mitochondrial Dysfunction.

Authors:  Yu-Lin Wang; Chung-Ching Chio; Shu-Chun Kuo; Chao-Hung Yeh; Jui-Ti Ma; Wen-Pin Liu; Mao-Tsun Lin; Kao-Chang Lin; Ching-Ping Chang
Journal:  Mol Neurobiol       Date:  2022-03-09       Impact factor: 5.590

Review 8.  Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease.

Authors:  Jianhua Zhang; Matilda Lillian Culp; Jason G Craver; Victor Darley-Usmar
Journal:  J Neurochem       Date:  2018-02-14       Impact factor: 5.372

Review 9.  mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder.

Authors:  M Perluigi; F Di Domenico; E Barone; D A Butterfield
Journal:  Free Radic Biol Med       Date:  2021-04-30       Impact factor: 8.101

10.  Microarray analysis of verbenalin-treated human amniotic epithelial cells reveals therapeutic potential for Alzheimer's Disease.

Authors:  Farhana Ferdousi; Shinji Kondo; Kazunori Sasaki; Yoshiaki Uchida; Nobuhiro Ohkohchi; Yun-Wen Zheng; Hiroko Isoda
Journal:  Aging (Albany NY)       Date:  2020-03-29       Impact factor: 5.955
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