Literature DB >> 27804226

In vivo terahertz reflection imaging of human scars during and after the healing process.

Shuting Fan1, Benjamin S Y Ung2, Edward P J Parrott2, Vincent P Wallace1, Emma Pickwell-MacPherson2.   

Abstract

We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophic scar. We found that the contrast in the absorption coefficient became less prominent after a few months post-injury, but that the contrast in the refractive index was still significant even months post-injury. Our results demonstrate the capability of terahertz imaging to quantitatively measure subtle changes in skin properties and this may be useful for improving scar treatment and management.
© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  scar; terahertz biomedical imaging; terahertz time-domain spectroscopy; wound healing

Mesh:

Year:  2016        PMID: 27804226     DOI: 10.1002/jbio.201600171

Source DB:  PubMed          Journal:  J Biophotonics        ISSN: 1864-063X            Impact factor:   3.207


  5 in total

1.  THz in vivo measurements: the effects of pressure on skin reflectivity.

Authors:  Jiarui Wang; Rayko I Stantchev; Qiushuo Sun; Tor-Wo Chiu; Anil T Ahuja; Emma Pickwell MacPherson
Journal:  Biomed Opt Express       Date:  2018-11-26       Impact factor: 3.732

Review 2.  Recent advances in terahertz technology for biomedical applications.

Authors:  Qiushuo Sun; Yuezhi He; Kai Liu; Shuting Fan; Edward P J Parrott; Emma Pickwell-MacPherson
Journal:  Quant Imaging Med Surg       Date:  2017-06

Review 3.  A Review of Feasible Applications of THz Waves in Medical Diagnostics and Treatments.

Authors:  Tahereh Amini; Fazel Jahangiri; Zoha Ameri; Mohammad Amin Hemmatian
Journal:  J Lasers Med Sci       Date:  2021-12-30

4.  Monitoring the molecular composition of live cells exposed to electric pulses via label-free optical methods.

Authors:  Antoine Azan; Marianne Grognot; Tomás García-Sánchez; Lucie Descamps; Valérie Untereiner; Olivier Piot; Guilhem Gallot; Lluis M Mir
Journal:  Sci Rep       Date:  2020-06-26       Impact factor: 4.379

5.  Critical Factors for In Vivo Measurements of Human Skin by Terahertz Attenuated Total Reflection Spectroscopy.

Authors:  Lixia Wang; Sayon Guilavogui; Henghui Yin; Yiping Wu; Xiaofei Zang; Jingya Xie; Li Ding; Lin Chen
Journal:  Sensors (Basel)       Date:  2020-07-30       Impact factor: 3.576

  5 in total

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