Literature DB >> 27803600

Use of low-value radiotherapy practices in Canada: an analysis of provincial cancer registry data.

K Tran1, R Rahal1, M Brundage2, S Fung1, C Louzado1, M Milosevic3, J Xu1, H Bryant4.   

Abstract

BACKGROUND: As part of Choosing Wisely Canada (a national campaign to encourage patient-provider conversations about unnecessary medical tests, treatments, and procedures), a list of ten oncology practices that could be low-value in some instances was developed. Of those practices, two were specific to radiation therapy (rt): conventional fractionation as part of breast-conserving therapy (bct) for women with early-stage breast cancer, and multifraction radiation for palliation of uncomplicated painful bone metastases. Here, we report baseline findings for the current utilization rates of those two rt practices in Canada.
RESULTS: The use of conventional fractionation as part of bct varied substantially from province to province. Of women 50 years of age and older, between 8.8% (Alberta) and 36.5% (Saskatchewan) received radiation in 25 fractions (excluding boost irradiation) as part of bct. The use of hypofractionated rt (that is, 16 fractions excluding boost irradiation)-a preferred approach for many patients-was more common in all 6 reporting provinces, ranging from 43.2% in Saskatchewan to 94.7% in Prince Edward Island. The use of multifraction rt for palliation of bone metastases also varied from province to province, ranging from 40.3% in British Columbia to 69.0% in Saskatchewan. The most common number of fractions delivered to bone metastases was 1, at 50.2%; the second most common numbers were 2-5 fractions, at 41.7%.
CONCLUSIONS: Understanding variation in the use of potentially low-value rt practices can help to inform future strategies to promote higher-value care, which balances high-quality care with the efficient use of limited system resources. Further work is needed to understand the factors contributing to the interprovincial variation observed and to develop benchmarks for the appropriate rate of use of these rt practices.

Entities:  

Keywords:  Breast cancer; appropriateness; bone metastasis; patterns of care; radiation

Year:  2016        PMID: 27803600      PMCID: PMC5081012          DOI: 10.3747/co.23.3359

Source DB:  PubMed          Journal:  Curr Oncol        ISSN: 1198-0052            Impact factor:   3.677


  24 in total

1.  Palliation of bone metastases: a survey of patterns of practice among Canadian radiation oncologists.

Authors:  E Chow; C Danjoux; R Wong; E Szumacher; E Franssen; K Fung; J Finkelstein; L Andersson; R Connolly
Journal:  Radiother Oncol       Date:  2000-09       Impact factor: 6.280

2.  Choosing Wisely Canada cancer list: ten low-value or harmful practices that should be avoided in cancer care.

Authors:  Gunita Mitera; Craig Earle; Steven Latosinsky; Christopher Booth; Andrea Bezjak; Christine Desbiens; Guila Delouya; Kara Laing; Natasha Camuso; Geoff Porter
Journal:  J Oncol Pract       Date:  2015-05       Impact factor: 3.840

Review 3.  Fractionation for whole breast irradiation: an American Society for Radiation Oncology (ASTRO) evidence-based guideline.

Authors:  Benjamin D Smith; Soren M Bentzen; Candace R Correa; Carol A Hahn; Patricia H Hardenbergh; Geoffrey S Ibbott; Beryl McCormick; Julie R McQueen; Lori J Pierce; Simon N Powell; Abram Recht; Alphonse G Taghian; Frank A Vicini; Julia R White; Bruce G Haffty
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-07-16       Impact factor: 7.038

4.  Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials.

Authors: 
Journal:  N Engl J Med       Date:  1995-11-30       Impact factor: 91.245

5.  Fractionation of Palliative Radiation Therapy for Bone Metastases in Ontario: Do Practice Guidelines Guide Practice?

Authors:  Allison Ashworth; Weidong Kong; Edward Chow; William J Mackillop
Journal:  Int J Radiat Oncol Biol Phys       Date:  2015-08-03       Impact factor: 7.038

Review 6.  Palliative radiotherapy trials for bone metastases: a systematic review.

Authors:  Edward Chow; Kristin Harris; Grace Fan; May Tsao; Wai M Sze
Journal:  J Clin Oncol       Date:  2007-04-10       Impact factor: 44.544

7.  International patterns of practice in palliative radiotherapy for painful bone metastases: evidence-based practice?

Authors:  Alysa Fairchild; Elizabeth Barnes; Sunita Ghosh; Edgar Ben-Josef; Daniel Roos; William Hartsell; Tanya Holt; Jackson Wu; Nora Janjan; Edward Chow
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-05-21       Impact factor: 7.038

8.  The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials.

Authors:  Joanne S Haviland; J Roger Owen; John A Dewar; Rajiv K Agrawal; Jane Barrett; Peter J Barrett-Lee; H Jane Dobbs; Penelope Hopwood; Pat A Lawton; Brian J Magee; Judith Mills; Sandra Simmons; Mark A Sydenham; Karen Venables; Judith M Bliss; John R Yarnold
Journal:  Lancet Oncol       Date:  2013-09-19       Impact factor: 41.316

Review 9.  Review of patterns of practice and patients' preferences in the treatment of bone metastases with palliative radiotherapy.

Authors:  Nicole M E Bradley; Janice Husted; Michael Sai Lai Sey; Amna F Husain; Emily Sinclair; Kristin Harris; Edward Chow
Journal:  Support Care Cancer       Date:  2006-11-09       Impact factor: 3.359

10.  Radiotherapy fractionation for the palliation of uncomplicated painful bone metastases - an evidence-based practice guideline.

Authors:  Jackson Sai-Yiu Wu; Rebecca K S Wong; Nancy S Lloyd; Mary Johnston; Andrea Bezjak; Timothy Whelan
Journal:  BMC Cancer       Date:  2004-10-04       Impact factor: 4.430

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  6 in total

Review 1.  A scoping review characterizing "Choosing Wisely®" recommendations for breast cancer management.

Authors:  Hely Shah; Julian Surujballi; Arif Ali Awan; Brian Hutton; Angel Arnaout; Risa Shorr; Lisa Vandermeer; Mashari Jemaan Alzahrani; Mark Clemons
Journal:  Breast Cancer Res Treat       Date:  2020-11-06       Impact factor: 4.872

2.  Screening for new primary cancers in patients with metastatic breast cancer: a provincial analysis of the Choosing Wisely Canada recommendations.

Authors:  M Tesch; K Laing
Journal:  Curr Oncol       Date:  2019-06-01       Impact factor: 3.677

3.  Does dissemination of guidelines alone increase the use of palliative single-fraction radiotherapy? Initial report of a longitudinal change management campaign at a provincial cancer program.

Authors:  J O Kim; N Hanumanthappa; Y T Chung; J Beck; R Koul; B Bashir; A Cooke; A Dubey; J Butler; M Nashed; W Hunter; A Ong
Journal:  Curr Oncol       Date:  2020-08-01       Impact factor: 3.677

4.  Preliminary toxicity results using partial breast 3D-CRT with once daily hypo-fractionation and deep inspiratory breath hold.

Authors:  Roman O Kowalchuk; Kara D Romano; Daniel M Trifiletti; Sunil W Dutta; Timothy N Showalter; Monica M Morris
Journal:  Radiat Oncol       Date:  2018-07-27       Impact factor: 3.481

5.  Do Sustainable Palliative Single Fraction Radiotherapy Practices Proliferate or Perish 2 Years after a Knowledge Translation Campaign?

Authors:  Shaheer Shahhat; Nikesh Hanumanthappa; Youn Tae Chung; James Beck; Rashmi Koul; Bashir Bashir; Andrew Cooke; Arbind Dubey; Jim Butler; Maged Nashed; William Hunter; Aldrich D Ong; Shrinivas Rathod; Kim Tran; Julian O Kim
Journal:  Curr Oncol       Date:  2022-07-19       Impact factor: 3.109

6.  Are radiation oncologists following guidelines? An audit of practice in patients with uncomplicated bone metastases.

Authors:  Vanessa Di Lalla; Bernard Fortin; Catherine Pembroke; Carolyn Freeman; Michael Yassa; Tarek Hijal
Journal:  Tech Innov Patient Support Radiat Oncol       Date:  2019-01-17
  6 in total

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