Literature DB >> 27801977

Immune reconstitution inflammatory syndrome in HIV infection: taking the bad with the good.

C-S Wong1, E S Richards1, L Pei1, I Sereti1.   

Abstract

In this review, we will describe the immunopathogies of immune reconstitution inflammatory syndrome, IRIS. IRIS occurs in a small subset of HIV patient, initiating combination antiretroviral therapy (ART), where immune reconstitution becomes dysregulated, resulting in an overly robust antigen-specific inflammatory reaction. We will discuss IRIS in terms of the associated coinfections: mycobacteria, cryptococci, and viruses. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

Entities:  

Keywords:  zzm321990HIVzzm321990; coinfection; immune reconstitution; immunology; lymphopenia; microbiology

Mesh：

Substances：

Year:  2016        PMID： 27801977      PMCID： PMC5411339          DOI： 10.1111/odi.12606

Source DB:  PubMed          Journal:  Oral Dis        ISSN： 1354-523X            Impact factor:   3.511


  60 in total

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Journal:  AIDS Res Ther       Date:  2012-03-09       Impact factor: 2.250

3.  Integration of antiretroviral therapy with tuberculosis treatment.

Authors:  Salim S Abdool Karim; Kogieleum Naidoo; Anneke Grobler; Nesri Padayatchi; Cheryl Baxter; Andrew L Gray; Tanuja Gengiah; Santhanalakshmi Gengiah; Anushka Naidoo; Niraksha Jithoo; Gonasagrie Nair; Wafaa M El-Sadr; Gerald Friedland; Quarraisha Abdool Karim
Journal:  N Engl J Med       Date:  2011-10-20       Impact factor: 91.245

4.  Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3.

Authors:  L Jussila; R Valtola; T A Partanen; P Salven; P Heikkilä; M T Matikainen; R Renkonen; A Kaipainen; M Detmar; E Tschachler; R Alitalo; K Alitalo
Journal:  Cancer Res       Date:  1998-04-15       Impact factor: 12.701

5.  Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice.

Authors:  Daniel L Barber; Katrin D Mayer-Barber; Lis R V Antonelli; Mark S Wilson; Sandra White; Patricia Caspar; Sara Hieny; Irini Sereti; Alan Sher
Journal:  Blood       Date:  2010-07-23       Impact factor: 22.113

Review 6.  Biomarkers in immune reconstitution inflammatory syndrome: signals from pathogenesis.

Authors:  Irini Sereti; Alison J Rodger; Martyn A French
Journal:  Curr Opin HIV AIDS       Date:  2010-11       Impact factor: 4.283

7.  Valganciclovir therapy for immune recovery uveitis complicated by macular edema.

Authors:  Brian R Kosobucki; Daniel E Goldberg; Kenichiro Bessho; Hyoung J Koh; Nuttawut Rodanant; Laurie Labree; Lingyun Cheng; Rachel D Schrier; Stanley P Azen; William R Freeman
Journal:  Am J Ophthalmol       Date:  2004-04       Impact factor: 5.258

8.  Intraocular viral and immune pathogenesis of immune recovery uveitis in patients with healed cytomegalovirus retinitis.

Authors:  Rachel D Schrier; Mi-Kyoung Song; Irene L Smith; Marietta P Karavellas; Dirk-Uwe Bartsch; Francesca J Torriani; Claudio R Garcia; William R Freeman
Journal:  Retina       Date:  2006-02       Impact factor: 4.256

9.  Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage.

Authors:  Claire Dunn; Maurizia Brunetto; Gary Reynolds; Theodoros Christophides; Patrick T Kennedy; Pietro Lampertico; Abhishek Das; A Ross Lopes; Persephone Borrow; Kevin Williams; Elizabeth Humphreys; Simon Afford; David H Adams; Antonio Bertoletti; Mala K Maini
Journal:  J Exp Med       Date:  2007-03-12       Impact factor: 14.307

10.  Efficacy and Safety of Antiretroviral Therapy Initiated One Week after Tuberculosis Therapy in Patients with CD4 Counts < 200 Cells/μL: TB-HAART Study, a Randomized Clinical Trial.

Authors:  Wondwossen Amogne; Getachew Aderaye; Abiy Habtewold; Getnet Yimer; Eyasu Makonnen; Alemayhu Worku; Anders Sonnerborg; Eleni Aklillu; Lars Lindquist
Journal:  PLoS One       Date:  2015-05-12       Impact factor: 3.240
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  1 in total

1.  Classical complement and inflammasome activation converge in CD14highCD16- monocytes in HIV associated TB-immune reconstitution inflammatory syndrome.

Authors:  Silvia Lucena Lage; Chun-Shu Wong; Eduardo Pinheiro Amaral; Daniel Sturdevant; Denise C Hsu; Adam Rupert; Eleanor M P Wilson; S Sonia Qasba; Nuha Sultana Naqvi; Elizabeth Laidlaw; Andrea Lisco; Maura Manion; Irini Sereti
Journal:  PLoS Pathog       Date:  2021-03-31       Impact factor: 6.823
  1 in total

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