Literature DB >> 27801739

18F-Florbetaben: A New Tool for Amyloidosis Staging?

Emmanuel D'Estanque1, Benjamin Chambert, Olivier Moranne, Pierre Olivier Kotzki, Vincent Boudousq.   

Abstract

We report the case of a 73-year-old man with a documented (renal biopsy) light-chain amyloidosis (AL) imaged with F-AV-1 (F-florbetaben) compared with a volunteer. A cardiac amyloidosis was suspected. As it was an AL and not a transthyretin amyloidosis, F-FDG and F-florbetaben PET/CT were preferred to bone scan. F-FDG scintigraphy showed a focal cardiac hypermetabolism. In addition of the heart, F-florbetaben scintigraphy showed an intense spleen and thyroid pathologic uptake and a moderate salivary gland and kidney uptake. F-florbetaben PET/CT appears to be useful for staging systemic amyloidosis.

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Year:  2017        PMID： 27801739     DOI： 10.1097/RLU.0000000000001434

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN： 0363-9762            Impact factor:   7.794


  5 in total

1.  [18F]Florbetaben PET-CT confirms AL amyloidosis in a patient with Waldenström's Macroglobulinemia.

Authors:  Thomas A Fox; Michael Lunn; Ashutosh Wechalekar; Jamshed Bomanji; Simon Wan; Shirley D'Sa
Journal:  Haematologica       Date:  2018-04-12       Impact factor: 9.941

2.  Cardiac amyloidosis imaging with amyloid positron emission tomography: A systematic review and meta-analysis.

Authors:  Yong Joong Kim; Sejin Ha; Yong-Il Kim
Journal:  J Nucl Cardiol       Date:  2018-07-18       Impact factor: 5.952

Review 3.  Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: clinical presentation, diagnosis, management and emerging therapies.

Authors:  Ilia G Halatchev; Jingsheng Zheng; Jiafu Ou
Journal:  J Thorac Dis       Date:  2018-03       Impact factor: 2.895

4.  Visualization of multiple organ amyloid involvement in systemic amyloidosis using 11C-PiB PET imaging.

Authors:  Naoki Ezawa; Nagaaki Katoh; Kazuhiro Oguchi; Tsuneaki Yoshinaga; Masahide Yazaki; Yoshiki Sekijima
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-09-10       Impact factor: 9.236

5.  18F-florbetaben whole-body PET/MRI for evaluation of systemic amyloid deposition.

Authors:  Lucia Baratto; Sonya Youngju Park; Negin Hatami; Praveen Gulaka; Shreyas Vasanawala; Thomas Koshy Yohannan; Robert Herfkens; Ronald Witteles; Andrei Iagaru
Journal:  EJNMMI Res       Date:  2018-07-24       Impact factor: 3.138
  5 in total

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