Nancy E Avis1, Alicia Colvin, Arun S Karlamangla, Sybil Crawford, Rachel Hess, L Elaine Waetjen, Maria Brooks, Ping G Tepper, Gail A Greendale. 1. 1Department of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, NC 2Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, PA 3Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 4Department of Medicine, University of Massachusetts Medical Center, Worcester, MA 5University of Utah School of the Health Sciences, Salt Lake City, UT 6Department of Obstetrics and Gynecology, University of California, Davis School of Medicine, Davis, CA.
Abstract
OBJECTIVE: The aim of the study was to identify whether there is a decline in sexual functioning related to the menopausal transition or to hysterectomy. METHODS: In a cohort of 1,390 women aged 42 to 52, with intact uterus and at least one ovary, not using hormone therapy, and pre- or early perimenopausal at baseline, we fit piecewise linear growth curves to 5,798 repeated measurements (seven visits spanning 14.5 y) of a sexual functioning score (range, 5-25) as a function of time relative to date of final menstrual period (FMP) or hysterectomy. RESULTS: Mean sexual functioning at baseline in women with a dateable FMP was 18.0 (SD, 3.4). There was no change in sexual function until 20 months before the FMP. From 20 months before until 1 year after the FMP, sexual function decreased by 0.35 annually (95% CI, -0.44 to -0.26) and continued to decline more than 1 year after the FMP, but at a slower rate (-0.13 annually, 95% CI, -0.17 to -0.10). The decline was smaller in African Americans and larger in Japanese than whites. Vaginal dryness, lubricant use, depressive symptoms, or anxiety did not explain decline in sexual function. Women who had a hysterectomy before the FMP did not show a decline in sexual function before hysterectomy, but scores declined afterward (0.21 annually, 95% CI, -0.28 to -0.14). CONCLUSIONS: Decline in sexual function became apparent 20 months before FMP and slowed 1 year after FMP through 5 years afterward. A decline in sexual function was observed immediately after hysterectomy and persisted for the 5 years of observation.
OBJECTIVE: The aim of the study was to identify whether there is a decline in sexual functioning related to the menopausal transition or to hysterectomy. METHODS: In a cohort of 1,390 women aged 42 to 52, with intact uterus and at least one ovary, not using hormone therapy, and pre- or early perimenopausal at baseline, we fit piecewise linear growth curves to 5,798 repeated measurements (seven visits spanning 14.5 y) of a sexual functioning score (range, 5-25) as a function of time relative to date of final menstrual period (FMP) or hysterectomy. RESULTS: Mean sexual functioning at baseline in women with a dateable FMP was 18.0 (SD, 3.4). There was no change in sexual function until 20 months before the FMP. From 20 months before until 1 year after the FMP, sexual function decreased by 0.35 annually (95% CI, -0.44 to -0.26) and continued to decline more than 1 year after the FMP, but at a slower rate (-0.13 annually, 95% CI, -0.17 to -0.10). The decline was smaller in African Americans and larger in Japanese than whites. Vaginal dryness, lubricant use, depressive symptoms, or anxiety did not explain decline in sexual function. Women who had a hysterectomy before the FMP did not show a decline in sexual function before hysterectomy, but scores declined afterward (0.21 annually, 95% CI, -0.28 to -0.14). CONCLUSIONS: Decline in sexual function became apparent 20 months before FMP and slowed 1 year after FMP through 5 years afterward. A decline in sexual function was observed immediately after hysterectomy and persisted for the 5 years of observation.
Authors: Ellen B Gold; Alicia Colvin; Nancy Avis; Joyce Bromberger; Gail A Greendale; Lynda Powell; Barbara Sternfeld; Karen Matthews Journal: Am J Public Health Date: 2006-05-30 Impact factor: 9.308
Authors: Tatjana Gazibara; Selmina Nurkovic; Nikolina Kovacevic; Ilma Kurtagic; Biljana Rancic; Sanja Radovanovic; Branislav Milosevic; Milan Terzic; Jelena Dotlic Journal: Qual Life Res Date: 2017-06-03 Impact factor: 4.147
Authors: Samar R El Khoudary; Gail Greendale; Sybil L Crawford; Nancy E Avis; Maria M Brooks; Rebecca C Thurston; Carrie Karvonen-Gutierrez; L Elaine Waetjen; Karen Matthews Journal: Menopause Date: 2019-10 Impact factor: 2.953