Literature DB >> 27797941

PGAM5: a new player in immune-mediated liver injury.

Anup Ramachandran1, Hartmut Jaeschke1.   

Abstract

Entities:  

Keywords:  AUTOIMMUNE HEPATITIS; CELL DEATH

Mesh：

Substances：

Year:  2016        PMID： 27797941      PMCID： PMC5479066          DOI： 10.1136/gutjnl-2016-312775

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


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  10 in total

1.  RIP kinases initiate programmed necrosis.

Authors:  Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Journal:  J Mol Cell Biol       Date:  2009-08-13       Impact factor: 6.216

2.  The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways.

Authors:  Zhigao Wang; Hui Jiang; She Chen; Fenghe Du; Xiaodong Wang
Journal:  Cell       Date:  2012-01-20       Impact factor: 41.582

3.  Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in mice.

Authors:  Anup Ramachandran; Mitchell R McGill; Yuchao Xie; Hong-Min Ni; Wen-Xing Ding; Hartmut Jaeschke
Journal:  Hepatology       Date:  2013-10-11       Impact factor: 17.425

4.  Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1.

Authors:  Kohsuke Takeda; Yoshiko Komuro; Teruyuki Hayakawa; Haruka Oguchi; Yosuke Ishida; Shiori Murakami; Takuya Noguchi; Hideyuki Kinoshita; Yusuke Sekine; Shun-ichiro Iemura; Tohru Natsume; Hidenori Ichijo
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-09       Impact factor: 11.205

5.  PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury.

Authors:  Gui-Wei He; Claudia Günther; Andreas E Kremer; Veronika Thonn; Kerstin Amann; Christopher Poremba; Markus F Neurath; Stefan Wirtz; Christoph Becker
Journal:  Gut       Date:  2016-08-26       Impact factor: 23.059

6.  Apoptosis Inducing Factor Binding Protein PGAM5 Triggers Mitophagic Cell Death That Is Inhibited by the Ubiquitin Ligase Activity of X-Linked Inhibitor of Apoptosis.

Authors:  Audrey M Lenhausen; Amanda S Wilkinson; Eric M Lewis; Kaitlin M Dailey; Andrew J Scott; Shahzeb Khan; John C Wilkinson
Journal:  Biochemistry       Date:  2016-06-02       Impact factor: 3.162

7.  The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.

Authors:  Kenta Moriwaki; Nivea Farias Luz; Sakthi Balaji; Maria Jose De Rosa; Carey L O'Donnell; Peter J Gough; John Bertin; Raymond M Welsh; Francis Ka-Ming Chan
Journal:  J Immunol       Date:  2015-11-18       Impact factor: 5.422

8.  Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Authors:  Young Jun Kang; Bo-Ram Bang; Kyung Ho Han; Lixin Hong; Eun-Jin Shim; Jianhui Ma; Richard A Lerner; Motoyuki Otsuka
Journal:  Nat Commun       Date:  2015-09-18       Impact factor: 14.919

9.  The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress.

Authors:  Shiori Sekine; Akari Yao; Kazuki Hattori; Sho Sugawara; Isao Naguro; Masato Koike; Yasuo Uchiyama; Kohsuke Takeda; Hidenori Ichijo
Journal:  EBioMedicine       Date:  2016-01-29       Impact factor: 8.143

10.  Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.

Authors:  Wei Lu; Junhui Sun; Jeong Seon Yoon; Yan Zhang; Lixin Zheng; Elizabeth Murphy; Mark P Mattson; Michael J Lenardo
Journal:  PLoS One       Date:  2016-01-25       Impact factor: 3.240
  10 in total
  2 in total

1.  Drp1-mediated mitochondrial fission promotes carbon tetrachloride-induced hepatic fibrogenesis in mice.

Authors:  Shulin Shan; Zhidan Liu; Shuai Wang; Zhaoxiong Liu; Zhengcheng Huang; Yiyu Yang; Cuiqin Zhang; Fuyong Song
Journal:  Toxicol Res (Camb)       Date:  2022-05-23       Impact factor: 2.680

2.  High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients.

Authors:  Jingjing Cheng; Dong Qian; Xiaofeng Ding; Tianqiang Song; Muyan Cai; Yuwen Wang; Jinlin Zhao; Zhuang Liu; Zhiqiang Wu; Qingsong Pang; Li Zhu; Ping Wang; Xishan Hao; Zhiyong Yuan
Journal:  Cell Death Dis       Date:  2018-09-24       Impact factor: 8.469
  2 in total

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