Literature DB >> 27797841

Cotrimoxazole treats fluoroquinolone-resistant Salmonella typhi H58 infection.

Manan Karki1, Sarbagya Pandit1, Stephen Baker2, Buddha Basnyat1.   

Abstract

A woman aged 20 years presented with fever and no localising signs. She was treated with cotrimoxazole and the subsequent blood culture was positive for Salmonella typhi (S. typhi), which was resistant to fluoroquinolones but susceptible to cotrimoxazole. Genotyping identified an FQ-R subclade of H58 S. typhi Fever clearance time was 4 days after starting the antibiotics, and no relapses were noted on 2 months of follow-up. This inexpensive, well-known and easily available antimicrobial could be suitably redeployed for fluoroquinolone-resistant enteric fever in South Asia. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID： 27797841      PMCID： PMC5093802          DOI： 10.1136/bcr-2016-217223

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


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