Literature DB >> 2779565

Repair of a synthetic abasic site in DNA in a Xenopus laevis oocyte extract.

Y Matsumoto1, D F Bogenhagen.   

Abstract

Covalently closed circular DNA containing a synthetic analog of an abasic site at a unique position was used as a substrate to study DNA repair. Incubation of this DNA in Xenopus laevis oocyte extracts resulted in rapid cleavage of the DNA at the abasic site by a class II apurinic-apyrimidinic endonuclease, followed by complete repair within 40 min. Nicked circular DNAs persisted for several minutes before repair by an ATP-dependent DNA synthesis reaction. The repair-related DNA synthesis was localized within 3 or 4 nucleotides surrounding the abasic site. These results are consistent with the short-patch repair reported for DNA damage at heterogeneous sites in human cells (J. D. Regan and R. B. Setlow, Cancer Res. 34:3318-3325, 1974).

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Year:  1989        PMID： 2779565      PMCID： PMC362436          DOI： 10.1128/mcb.9.9.3750-3757.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  27 in total

1.  DNA binding activity from cultured human fibrolasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites.

Authors:  W A Deutsch; S Linn
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

2.  Mechanism of DNA cleavage and substrate recognition by a bovine apurinic endonuclease.

Authors:  B J Sanderson; C N Chang; A P Grollman; W D Henner
Journal:  Biochemistry       Date:  1989-05-02       Impact factor: 3.162

3.  Enzymatic insertion of purine bases into depurinated DNA in vitro.

Authors:  Z Livneh; D Elad; J Sperling
Journal:  Proc Natl Acad Sci U S A       Date:  1979-03       Impact factor: 11.205

4.  Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens.

Authors:  J D Regan; R B Setlow
Journal:  Cancer Res       Date:  1974-12       Impact factor: 12.701

5.  The bidirectional transfer of DNA and RNA to nitrocellulose or diazobenzyloxymethyl-paper.

Authors:  G E Smith; M D Summers
Journal:  Anal Biochem       Date:  1980-11-15       Impact factor: 3.365

6.  Fractionation of DNA fragments by polyethylene glycol induced precipitation.

Authors:  J T Lis
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

7.  Exonuclease III of Escherichia coli K-12, an AP endonuclease.

Authors:  S G Rogers; B Weiss
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

8.  Sequencing end-labeled DNA with base-specific chemical cleavages.

Authors:  A M Maxam; W Gilbert
Journal:  Methods Enzymol       Date:  1980       Impact factor: 1.600

9.  Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

Authors:  W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

10.  Interaction of mammalian deoxyribonuclease V, a double strand 3' to 5' and 5' to 3' exonuclease, with deoxyribonucleic acid polymerase-beta from the Novikoff hepatoma.

Authors:  D W Mosbaugh; R R Meyer
Journal:  J Biol Chem       Date:  1980-11-10       Impact factor: 5.157
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  19 in total

1.  An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions.

Authors:  H Kamiya; M Suzuki; Y Komatsu; H Miura; K Kikuchi; T Sakaguchi; N Murata; C Masutani; F Hanaoka; E Ohtsuka
Journal:  Nucleic Acids Res       Date:  1992-09-11       Impact factor: 16.971

2.  DNA damage response of cloned DNA beta-polymerase promoter is blocked in mutant cell lines deficient in protein kinase A.

Authors:  E W Englander; S H Wilson
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

3.  Repair and recombination of X-irradiated plasmids in Xenopus laevis oocytes.

Authors:  S E Sweigert; D Carroll
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

4.  Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

Authors:  K Wiebauer; J Jiricny
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

5.  Repair of a synthetic abasic site involves concerted reactions of DNA synthesis followed by excision and ligation.

Authors:  Y Matsumoto; D F Bogenhagen
Journal:  Mol Cell Biol       Date:  1991-09       Impact factor: 4.272

6.  Deployment of DNA polymerases beta and lambda in single-nucleotide and multinucleotide pathways of mammalian base excision DNA repair.

Authors:  Upasna Thapar; Bruce Demple
Journal:  DNA Repair (Amst)       Date:  2019-02-04

7.  Generation of single-nucleotide repair patches following excision of uracil residues from DNA.

Authors:  G Dianov; A Price; T Lindahl
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

8.  Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector.

Authors:  M Takeshita; W Eisenberg
Journal:  Nucleic Acids Res       Date:  1994-05-25       Impact factor: 16.971

9.  The genome of Melanoplus sanguinipes entomopoxvirus.

Authors:  C L Afonso; E R Tulman; Z Lu; E Oma; G F Kutish; D L Rock
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

10.  Single-nucleotide and long-patch base excision repair of DNA damage in plants.

Authors:  Dolores Córdoba-Cañero; Teresa Morales-Ruiz; Teresa Roldán-Arjona; Rafael R Ariza
Journal:  Plant J       Date:  2009-08-08       Impact factor: 6.417
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