| Literature DB >> 27793882 |
Ammar Sukari1, Misako Nagasaka2, Ameer Al-Hadidi3, Lawrence G Lum4.
Abstract
Hanahan and Weinberg described six distinct biological properties of cancer cells that enable tumor growth and metastasis. These properties were referred to as the traditional hallmarks of cancer. Recent discoveries further elucidated hallmarks including evasion of immune destruction by tumor cells that disrupt anticancer response pathways. This review discusses cancer immunology and new treatment strategies aimed at restoration of antitumor immune responses. CopyrightEntities:
Keywords: CTLA4; Cancer immunology; PD1; PDL1; checkpoint inhibitor; immunotherapy
Mesh:
Year: 2016 PMID: 27793882 DOI: 10.21873/anticanres.11144
Source DB: PubMed Journal: Anticancer Res ISSN: 0250-7005 Impact factor: 2.480