Literature DB >> 27793875

Adult necrotising enterocolitis-pig-bel disease: a Pacific disease in London.

Justin Conrad Rosen Wormald1, Sanjay Dindyal1, Francesca Mellor1, Nebil Behar1.   

Abstract

Adult necrotising enterocolitis secondary Clostridium perfringens type C-pig-bel disease-is rarely seen outside of Pacific populations, with the highest incidence being in Papau New Guinea. We present the first reported case of pig-bel disease in a previously well patient without diabetes following food poisoning since 1996. In this case, the enterotoxin-induced disease necessitated emergency laparotomy and bowel resection following the failure of medical treatment and worsening septic shock. We hypothesise that obstruction secondary to a sigmoid diverticular stricture complicated by infection-related oedema led to colonic stasis and rapid progression of disease and bowel loss. Following bowel resection, several parenteral antibiotic agents and prolonged intensive care, this patient survived this severe infective process and was discharged home. 2016 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2016        PMID: 27793875      PMCID: PMC5093345          DOI: 10.1136/bcr-2016-217903

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  A review of diarrhoea aetiology in Papua New Guinea, 1995-2012.

Authors:  Pamela J Toliman; Carlton Guwada; Kevin W Sou
Journal:  P N G Med J       Date:  2013 Sep-Dec

Review 2.  Recent progress in understanding the pathogenesis of Clostridium perfringens type C infections.

Authors:  F A Uzal; B A McClane
Journal:  Vet Microbiol       Date:  2011-02-26       Impact factor: 3.293

3.  Pathogenesis of Clostridium perfringens infection: mechanisms and mediators of shock.

Authors:  D L Stevens; A E Bryant
Journal:  Clin Infect Dis       Date:  1997-09       Impact factor: 9.079

Review 4.  Fatal enteritis necroticans (pigbel) in a diabetic adult.

Authors:  Lizhen Gui; Charu Subramony; Jonathan Fratkin; Michael D Hughson
Journal:  Mod Pathol       Date:  2002-01       Impact factor: 7.842

5.  Enteritis necroticans (pigbel) in a diabetic child.

Authors:  T M Petrillo; C M Beck-Sagué; J G Songer; C Abramowsky; J D Fortenberry; L Meacham; A G Dean; H Lee; D M Bueschel; S R Nesheim
Journal:  N Engl J Med       Date:  2000-04-27       Impact factor: 91.245

Review 6.  Necrotizing enterocolitis associated with clostridium perfringens type A in previously healthy north american adults.

Authors:  Jeremy Sobel; Charles G Mixter; Priti Kolhe; Amita Gupta; Jeannette Guarner; Sherif Zaki; Neil A Hoffman; J Glenn Songer; Maurice Fremont-Smith; Marc Fischer; George Killgore; Phyllis H Britz; Clifford MacDonald
Journal:  J Am Coll Surg       Date:  2005-07       Impact factor: 6.113

7.  Pigbel-like syndrome in a vegetarian in Oxford.

Authors:  J M Farrant; Z Traill; C Conlon; B Warren; N Mortensen; F V Gleeson; D P Jewell
Journal:  Gut       Date:  1996-08       Impact factor: 23.059

8.  Enteritis necroticans 'pigbel' in a Japanese diabetic adult.

Authors:  Tomomichi Matsuda; Yuji Okada; Eiji Inagi; Yasushi Tanabe; Yozo Shimizu; Kazuo Nagashima; Jun Sakurai; Masahiro Nagahama; Shinya Tanaka
Journal:  Pathol Int       Date:  2007-09       Impact factor: 2.534

9.  Clostridium perfringens Type C Enterotoxemia.

Authors:  L Niilo
Journal:  Can Vet J       Date:  1988-08       Impact factor: 1.008

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.