OBJECTIVE: The aim of this study was to assess the mean of histamine concentration in food poisoning. DESIGN: Systematic review and meta-analysis of reports published between 1959 and 2013. STUDY SELECTION: Main criteria for inclusion of studies were: all report types that present outbreaks of "histamine poisoning' or "scombroid syndrome" from food, including histamine content and type of food. Health status of people involved must be nonpathological. RESULTS: Fifty-five (55) reports were included, these studies reported 103 incidents. All pooled analyses were based on random effect model; histamine mean concentration in poisoning samples was 1107.21 mg/kg with confidence interval for the meta-mean of 422.62-2900.78 mg/kg; heterogeneity index (I2) was 100% (P < 0.0001); prediction interval was 24.12-50822.78 mg/kg. Fish involved in histamine poisoning was mainly tuna or Istiophoridae species. No clues of association between concomitant conditions (female sex, alcohol consumption, previous medication, and consumption of histamine releasing food) and histamine poisoning, were highlighted. CONCLUSIONS: This is the first systematic review and meta-analysis that analyzes all the available data on histamine poisoning outbreaks evaluating the histamine concentration in food involved. Histamine mean concentration in poisoning samples was fairly high. Our study suffers from some limitations, which are intrinsic of the studies included, for instance the lack of a complete anamnesis of each poisoning episode. Protocol registration: Methods were specified in advance and have been published as a protocol in PROSPERO database (18/07/2012 -CRD42012002566).
OBJECTIVE: The aim of this study was to assess the mean of histamine concentration in food poisoning. DESIGN: Systematic review and meta-analysis of reports published between 1959 and 2013. STUDY SELECTION: Main criteria for inclusion of studies were: all report types that present outbreaks of "histaminepoisoning' or "scombroid syndrome" from food, including histamine content and type of food. Health status of people involved must be nonpathological. RESULTS: Fifty-five (55) reports were included, these studies reported 103 incidents. All pooled analyses were based on random effect model; histamine mean concentration in poisoning samples was 1107.21 mg/kg with confidence interval for the meta-mean of 422.62-2900.78 mg/kg; heterogeneity index (I2) was 100% (P < 0.0001); prediction interval was 24.12-50822.78 mg/kg. Fish involved in histaminepoisoning was mainly tuna or Istiophoridae species. No clues of association between concomitant conditions (female sex, alcohol consumption, previous medication, and consumption of histamine releasing food) and histaminepoisoning, were highlighted. CONCLUSIONS: This is the first systematic review and meta-analysis that analyzes all the available data on histaminepoisoning outbreaks evaluating the histamine concentration in food involved. Histamine mean concentration in poisoning samples was fairly high. Our study suffers from some limitations, which are intrinsic of the studies included, for instance the lack of a complete anamnesis of each poisoning episode. Protocol registration: Methods were specified in advance and have been published as a protocol in PROSPERO database (18/07/2012 -CRD42012002566).
Authors: Oriol Comas-Basté; Sònia Sánchez-Pérez; Maria Teresa Veciana-Nogués; Mariluz Latorre-Moratalla; María Del Carmen Vidal-Carou Journal: Biomolecules Date: 2020-08-14
Authors: Guillaume Velut; François Delon; Jean Paul Mérigaud; Christelle Tong; Guillaume Duflos; François Boissan; Stéphanie Watier-Grillot; Mickaël Boni; Clement Derkenne; Aissata Dia; Gaëtan Texier; Philippe Vest; Jean Baptiste Meynard; Pierre Edouard Fournier; Aurélie Chesnay; Vincent Pommier de Santi Journal: Euro Surveill Date: 2019-05
Authors: Cho Ryok Kang; Young Yun Kim; Jae In Lee; Hyun Don Joo; Sun Wha Jung; Sung-Il Cho Journal: J Korean Med Sci Date: 2018-08-01 Impact factor: 2.153