Literature DB >> 27790584

Comparative Evaluation of Efficacy of Three Different Herbal Toothpastes on Salivary Alkaline Phosphatase and Salivary Acid Phosphatase - A Randomized Controlled Trial.

Mahesh Khairnar1, Arun Dodamani2, G N Karibasappa3, Manjiri Deshmukh4, Rahul Naik5.   

Abstract

INTRODUCTION: Very few researches in the past have tried to evaluate the effect of herbal toothpaste on saliva and salivary constituents like alkaline phosphatase and acid phosphatase which play an important role in maintaining oral health. AIM: To evaluate and compare the effect of three different herbal toothpastes on Salivary Alkaline Phosphatase (ALP) and salivary Acid Phosphatase (ACP).
MATERIAL AND METHODS: The present study was a preliminary study conducted among 45 dental students (15 subjects in each group) in the age group of 19-21 years. Subjects in each group were randomly intervened with three different herbal toothpastes respectively (Group A - Patanjali Dant Kanti, Group B - Himalaya Complete Care and Group C - Vicco Vajradanti). Unstimulated saliva sample were collected before and after brushing and salivary ACP and salivary ALP levels were assessed at an interval of one week each for a period of four weeks starting from day one. Compiled data was analyzed using chi square test, paired t-test and ANOVA based on the nature of the obtained data.
RESULTS: All the three toothpastes showed significant (p<0.001) reduction in ACP and ALP levels at each interval. For patanjali toothpaste, the mean reduction was in the range of 2.55 - 2.62 IU/L for ACP and 2.94 - 2.99 IU/L for ALP. For Himalaya toothpaste, the mean reduction was in the range of 1.39 - 1.47 IU/L for ACP and 1.55 - 1.61 IU/L for ALP. For Vicco toothpaste, the mean reduction was in the range of 2.46 - 2.50 IU/L for ACP and 2.64 - 2.77 IU/L for ALP. Patanjali and Vicco toothpaste were significantly effective in reducing the levels of salivary ACP and ALP more than Himalaya toothpaste (p<0.05).
CONCLUSION: Herbal toothpastes, especially Dant Kanti and Vicco Vajradanti, showed significant reduction in levels of ACP and ALP resulting in overall improvement towards the oral health.

Entities:  

Keywords:  Dentifrices; Oral health; Saliva

Year:  2016        PMID: 27790584      PMCID: PMC5072084          DOI: 10.7860/JCDR/2016/20811.8542

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  12 in total

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Authors:  B H Goldstein; J B Epstein
Journal:  J Can Dent Assoc       Date:  2000-11       Impact factor: 1.316

Review 2.  The diagnostic applications of saliva--a review.

Authors:  Eliaz Kaufman; Ira B Lamster
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Review 3.  Saliva as a diagnostic fluid.

Authors:  Daniel Malamud
Journal:  Dent Clin North Am       Date:  2011-01

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Authors:  Mohankumar K P; Priya N K; Madhushankari G S
Journal:  J Int Oral Health       Date:  2013-04

5.  Multicentre study of allergic contact cheilitis from toothpastes.

Authors:  S Francalanci; A Sertoli; S Giorgini; P Pigatto; B Santucci; R Valsecchi
Journal:  Contact Dermatitis       Date:  2000-10       Impact factor: 6.600

6.  Emerging trends of herbal care in dentistry.

Authors:  Gunjan Kumar; Md Jalaluddin; Purnendu Rout; Rajat Mohanty; C L Dileep
Journal:  J Clin Diagn Res       Date:  2013-08-01

7.  Salivary enzymes as diagnostic markers for detection of gingival/periodontal disease and their correlation with the severity of the disease.

Authors:  Sarita Dabra; Kamalpreet China; Alka Kaushik
Journal:  J Indian Soc Periodontol       Date:  2012-07

8.  Assessment of the alkaline phosphatase level in gingival crevicular fluid, as a biomarker to evaluate the effect of scaling and root planing on chronic periodontitis: An in vivo study.

Authors:  Jimly James Kunjappu; Vinod Babu Mathew; Shashikanth Hegde; Rajesh Kashyap; Rajesh Hosadurga
Journal:  J Oral Maxillofac Pathol       Date:  2012-01

9.  Comparison between the Efficacy of Herbal and Conventional Dentifrices on Established Gingivitis.

Authors:  Abdulwahab I Al-Kholani
Journal:  Dent Res J (Isfahan)       Date:  2011

10.  Evaluating the levels of salivary alkaline and acid phosphatase activities as biochemical markers for periodontal disease: A case series.

Authors:  Sarita Dabra; Preetinder Singh
Journal:  Dent Res J (Isfahan)       Date:  2012-01
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