Literature DB >> 27790507

Fungal Infection in Thermal Burns: A Prospective Study in a Tertiary Care Centre.

Sanjeev Sharma1, Deepak Bajaj2, Pritika Sharma3.   

Abstract

INTRODUCTION: Burn Wound Infection (BWI) is primarily caused by aerobic bacteria followed by fungi, anaerobes and viruses. There has been a worldwide decrease in incidence of bacterial infections in burns due to better patient care and availability of effective antibiotics. Consequently, the fungal burn wound infection has shown an increasing trend. AIM: The aim of study was to assess the frequency of fungal infections in thermal burn wounds with respect to age of wounds, total body surface involved, depth of burns and to assess common fungal pathogens.
MATERIALS AND METHODS: The study was conducted on 50 patients admitted with thermal burn wounds having 20-60% burns in the surgical unit. Pus swab and scrapings were taken under local anaesthesia from each burn patient. Scrapings were put in a sterile container and sent to Mycology section of Microbiology department and were examined by direct microscopy and culture studies on Sabouraud's Dextrose Agar medium in the Mycology section of Microbiology department.
RESULTS: In our study, the incidence of fungal infection in burn wound patients came out to be 26%. The incidence of fungal infection increased with increase in Total Body Surface Area, (TBSA) increase in depth and age of burn. In our study, the maximum positive fungal cultures were seen in the third week of post-burn period. No positive culture was seen in the first week and 30.76% positive fugal cultures were seen in second post-burn week. Candida albicans was found to be the most common organism followed by Non-albicans Candida and Aspergillus.
CONCLUSION: It was concluded from the study that incidence of fungal infections in thermal burns increased with increase in post-burn period and with increasing depth and TBSA of burns. Candida albicans was found to be the most common fungus.

Entities:  

Keywords:  Burn wound infection; Fungal culture; Mycoses

Year:  2016        PMID: 27790507      PMCID: PMC5072007          DOI: 10.7860/JCDR/2016/20336.8445

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  14 in total

Review 1.  Fungal infections in burns: a comprehensive review.

Authors:  M F Struck; J Gille
Journal:  Ann Burns Fire Disasters       Date:  2013-09-30

2.  Opportunistic fungal infection of the burn wound with phycomycetes and Aspergillus. A clinical-pathologic review.

Authors:  H M Bruck; G Nash; D Foley; B A Pruitt
Journal:  Arch Surg       Date:  1971-05

3.  Candida in burns: risk factors and outcomes.

Authors:  Edwina C Moore; Alexander A Padiglione; Jason Wasiak; Eldho Paul; Heather Cleland
Journal:  J Burn Care Res       Date:  2010 Mar-Apr       Impact factor: 1.845

4.  Association of hyperglycemia with increased mortality after severe burn injury.

Authors:  D C Gore; D Chinkes; J Heggers; D N Herndon; S E Wolf; M Desai
Journal:  J Trauma       Date:  2001-09

Review 5.  Burn wound infections.

Authors:  Deirdre Church; Sameer Elsayed; Owen Reid; Brent Winston; Robert Lindsay
Journal:  Clin Microbiol Rev       Date:  2006-04       Impact factor: 26.132

Review 6.  Epidemiology of nosocomial fungal infections, with emphasis on Candida species.

Authors:  W R Jarvis
Journal:  Clin Infect Dis       Date:  1995-06       Impact factor: 9.079

7.  Incidence of systemic fungal infection and related mortality following severe burns.

Authors:  Clinton K Murray; Florence L Loo; Duane R Hospenthal; Leopoldo C Cancio; John A Jones; Seung H Kim; John B Holcomb; Charles E Wade; Steven E Wolf
Journal:  Burns       Date:  2008-08-08       Impact factor: 2.744

8.  Systemic Candida infection in burn patients: a case-control study of management patterns and outcomes.

Authors:  Amalia Cochran; Stephen E Morris; Linda S Edelman; Jeffrey R Saffle
Journal:  Surg Infect (Larchmt)       Date:  2002       Impact factor: 2.150

Review 9.  Emerging infections in burns.

Authors:  Ludwik K Branski; Ahmed Al-Mousawi; Haidy Rivero; Marc G Jeschke; Arthur P Sanford; David N Herndon
Journal:  Surg Infect (Larchmt)       Date:  2009-10       Impact factor: 2.150

10.  Positive fungal cultures in burn patients: a multicenter review.

Authors:  James Ballard; Linda Edelman; Jeffrey Saffle; Robert Sheridan; Richard Kagan; D Bracco; Leopoldo Cancio; Bruce Cairns; Rose Baker; Paula Fillari; Lucy Wibbenmeyer; David Voight; Tina Palmieri; David Greenhalgh; Nathan Kemalyan; Daniel Caruso
Journal:  J Burn Care Res       Date:  2008 Jan-Feb       Impact factor: 1.845

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  5 in total

Review 1.  Advancements in Regenerative Strategies Through the Continuum of Burn Care.

Authors:  Randolph Stone Ii; Shanmugasundaram Natesan; Christine J Kowalczewski; Lauren H Mangum; Nicholas E Clay; Ryan M Clohessy; Anders H Carlsson; David H Tassin; Rodney K Chan; Julie A Rizzo; Robert J Christy
Journal:  Front Pharmacol       Date:  2018-07-09       Impact factor: 5.810

2.  Prevalence, species distribution, and risk factors of fungal colonization and infection in patients at a burn intensive care unit in Vietnam.

Authors:  Be Nguyen Van Bang; Nguyen Thanh Xuan; Dinh Xuan Quang; Cao Ba Loi; Nguyen Thai Ngoc Minh; Nguyen Nhu Lam; Do Ngoc Anh; Truong Thi Thu Hien; Hoang Xuan Su; Le Tran-Anh
Journal:  Curr Med Mycol       Date:  2020-09

3.  Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants.

Authors:  Christin von Müller; Fionnuala Bulman; Lysett Wagner; Daniel Rosenberger; Alessandra Marolda; Oliver Kurzai; Petra Eißmann; Ilse D Jacobsen; Birgit Perner; Peter Hemmerich; Slavena Vylkova
Journal:  Sci Rep       Date:  2020-12-11       Impact factor: 4.379

4.  Different Infection Profiles and Antimicrobial Resistance Patterns Between Burn ICU and Common Wards.

Authors:  Yali Gong; Yuan Peng; Xiaoqiang Luo; Cheng Zhang; Yunlong Shi; Yixin Zhang; Jun Deng; Yizhi Peng; Gaoxing Luo; Haisheng Li
Journal:  Front Cell Infect Microbiol       Date:  2021-06-30       Impact factor: 5.293

5.  Invasive Candidiasis in Hospitalized Patients with Major Burns.

Authors:  Yi-Ling Lin; I-Chen Chen; Jung-Hsing Yen; Chih-Sheng Lai; Yueh-Chi Tsai; Chun-Te Lu; Cheng-Yeu Wu; Wei-Szu Lin; Ching-Heng Lin; Yung-Chieh Huang
Journal:  J Pers Med       Date:  2022-01-04
  5 in total

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