Literature DB >> 27790496

Unexplained Persistent Hyperglycaemia in a Type I Diabetes Patient - Is Injection Site Lipohypertrophy the Cause?

Ranjana Ajit Sahasrabudhe1, Tejas Yashwant Limaye2, Vidya Sanjay Gokhale3.   

Abstract

Type I diabetes patients depend on insulin injections. Proper injection technique is essential for good glycaemic control. Incorrect technique can also lead to local injection site adverse effects, commonest being lipohypertrophy. Hypoglycaemia, by far the most dreaded adverse effect of insulin, receives utmost focus in management of patients on insulin. Lipohypertrophy, on the other hand, is a relatively neglected adverse effect. It is necessary for health care providers to realize that it can also have serious clinical implications. We present a case of persistent unexplained hyperglycaemia in a Type I Diabetes Mellitus (TIDM) patient with severe injection site lipohypertropy. After switching to normal unused sites, her blood sugar levels improved, along with reduction in insulin requirement. The case highlights the importance of continuous patient education and alert monitoring by health care providers.

Entities:  

Keywords:  Insulin injection technique; Patient education; Site rotation

Year:  2016        PMID: 27790496      PMCID: PMC5071996          DOI: 10.7860/JCDR/2016/22215.8483

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

1.  Poor glycaemic control caused by insulin induced lipohypertrophy.

Authors:  Tahseen A Chowdhury; Valerie Escudier
Journal:  BMJ       Date:  2003-08-16

2.  Impaired absorption of insulin aspart from lipohypertrophic injection sites.

Authors:  Unn-Britt Johansson; Susanne Amsberg; Lena Hannerz; Regina Wredling; Ulf Adamson; Hans J Arnqvist; Per-Eric Lins
Journal:  Diabetes Care       Date:  2005-08       Impact factor: 19.112

3.  Prevalence of lipohypertrophy in insulin-treated diabetic patients and predisposing factors.

Authors:  H Hauner; B Stockamp; B Haastert
Journal:  Exp Clin Endocrinol Diabetes       Date:  1996       Impact factor: 2.949

4.  Incidence of lipohypertrophy in diabetic patients and a study of influencing factors.

Authors:  Bahar Vardar; Sevgi Kizilci
Journal:  Diabetes Res Clin Pract       Date:  2007-02-15       Impact factor: 5.602

Review 5.  Insulin absorption from lipodystrophic areas: a (neglected) source of trouble for insulin therapy?

Authors:  Lutz Heinemann
Journal:  J Diabetes Sci Technol       Date:  2010-05-01

Review 6.  Forum for Injection Technique (FIT), India: The Indian recommendations 2.0, for best practice in Insulin Injection Technique, 2015.

Authors:  Nikhil Tandon; Sanjay Kalra; Yatan Pal Singh Balhara; Manash P Baruah; Manoj Chadha; Hemraj B Chandalia; Subhankar Chowdhury; Kesavadev Jothydev; Prasanna K M Kumar; Madhu S V; Ambrish Mithal; Sonal Modi; Shailesh Pitale; Rakesh Sahay; Rishi Shukla; Annamalai Sundaram; Ambika G Unnikrishnan; Subhash K Wangnoo
Journal:  Indian J Endocrinol Metab       Date:  2015 May-Jun

7.  Role of self-care in management of diabetes mellitus.

Authors:  Saurabh Rambiharilal Shrivastava; Prateek Saurabh Shrivastava; Jegadeesh Ramasamy
Journal:  J Diabetes Metab Disord       Date:  2013-03-05
  7 in total
  1 in total

1.  Insulin-induced Lipohypertrophy in Patients with Type 1 Diabetes Mellitus Treated with an Insulin Pump.

Authors:  Damian Ucieklak; Sandra Mrozinska; Aleksandra Wojnarska; Maciej T Malecki; Tomasz Klupa; Bartłomiej Matejko
Journal:  Int J Endocrinol       Date:  2022-01-24       Impact factor: 3.257

  1 in total

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