Literature DB >> 27790306

Giant adrenal germ cell tumour in a 59-year-old woman.

Lei Chen1, Lu Fang1, Zhiqi Liu1, Dexin Yu1, Daming Wang1, Yi Wang1, Dongdong Xie1, Jie Min1, Demao Ding1, Tao Zhang1, Ci Zou1, Zhiqiang Zhang1.   

Abstract

Adrenal germ cell tumour is very rare. We report a case of a 59-year-old woman who presented with right flank discomfort. The laboratory examinations were normal and the chest computed tomography (CT) showed right pleural effusion. The abdominal CT scan revealed a large mass on the right adrenal gland. The patient underwent an adrenalectomy. Histopathologic examination and immunohistochemical findings were consistent with mixed germ cell tumour. Three months later following the operation, the patient was admitted to our hospital again with chest tightness and shortness of breath. The chest CT showed right pleural effusion recurrence and enlargement of mediastinal lymph nodes and right hilar lymph nodes. The patient had right supraclavicular lymphadenectasis on physical examination. Fine needle aspiration cytology from the supraclavicular lymph nodes showed groups of malignant tumour cells. The patient died within 6 months postoperatively. In this case, the lymph node pathway played an important role in the metastatic procedure.

Entities:  

Year:  2016        PMID: 27790306      PMCID: PMC5065414          DOI: 10.5489/cuaj.2904

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  17 in total

Review 1.  Extragonadal germ cell tumors and unrecognized germ cell tumors.

Authors:  J D Hainsworth; F A Greco
Journal:  Semin Oncol       Date:  1992-04       Impact factor: 4.929

2.  The second case of de novo intracranial germinoma association with Klinefelter's syndrome.

Authors:  Prasit Phowthongkum
Journal:  Surg Neurol       Date:  2006-09

3.  Mixed malignant germ cell tumour of third ventricle with hydrocephalus: a rare case with recurrence.

Authors:  Manjari Kishore; Vidya Monappa; Lakshmi Rao; Ranjini Kudva
Journal:  J Clin Diagn Res       Date:  2014-11-20

4.  Adrenal gland teratoma in a 40-year-old woman.

Authors:  M K Shrestha; S Lalchan
Journal:  Nepal Med Coll J       Date:  2010-09

5.  Extragonadal germ cell tumors are often associated with Klinefelter syndrome.

Authors:  David Aguirre; Karem Nieto; Minerva Lazos; Y Rocio Peña; Icela Palma; Susana Kofman-Alfaro; Gloria Queipo
Journal:  Hum Pathol       Date:  2006-04       Impact factor: 3.466

6.  A giant primary retroperitoneal mature cystic teratoma in right adrenal region in a 39-year-old female.

Authors:  Dong-Dong Tang; Xian-Sheng Zhang; Zong-Yao Hao; Jun Zhou; Chao-Zhao Liang
Journal:  Int J Clin Exp Med       Date:  2014-06-15

7.  Primary germ cell tumor of the mediastinum - presenting as a huge mass.

Authors:  Usha Dalal; Manjit Singh Jora; Ashwani K Dalal; Ashok K Attri; Rikki Singal; Samita Gupta
Journal:  Int J Prev Med       Date:  2014-02

8.  Mixed germ cell tumors of the ovary.

Authors:  D M Gershenson; G Del Junco; L J Copeland; F N Rutledge
Journal:  Obstet Gynecol       Date:  1984-08       Impact factor: 7.661

9.  Atypical extragonadal germ cell tumors.

Authors:  Mainak Deb; Suravi Mohanty; Anuradha Ananthamurthy; Isha Garg; Kanishka Das
Journal:  J Indian Assoc Pediatr Surg       Date:  2012-01

10.  Giant mature adrenal cystic teratoma in an infant.

Authors:  Ilhan Ciftci; Tugba Cihan; Yavuz Koksal; Serdar Ugras; Cengiz Erol
Journal:  Acta Inform Med       Date:  2013
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