Literature DB >> 2779013

Blockade of enkephalinergic and GABAergic mediated locomotion in the nucleus accumbens by muscimol in the ventral pallidum.

M C Austin1, P W Kalivas.   

Abstract

The mu-opioid agonist, DAGO, and the indirect GABAA antagonist, picrotoxin, produced a dose-dependent increase in horizontal motor activity following injection into the nucleus accumbens that was independent of dopamine release. Injection of muscimol into the ventral pallidum antagonizes the motor stimulant effect of dopamine agonists. It was shown that muscimol abolished the locomotor stimulant effect of DAGO microinjection into the nucleus accumbens, and partially antagonized the effect of picrotoxin.

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Year:  1989        PMID： 2779013     DOI： 10.1254/jjp.50.487

Source DB:  PubMed          Journal:  Jpn J Pharmacol        ISSN： 0021-5198


  13 in total

Review 1.  The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors.

Authors:  David H Root; Roberto I Melendez; Laszlo Zaborszky; T Celeste Napier
Journal:  Prog Neurobiol       Date:  2015-04-06       Impact factor: 11.685

2.  Lateral preoptic and ventral pallidal roles in locomotion and other movements.

Authors:  Suriya Subramanian; Rhett A Reichard; Hunter S Stevenson; Zachary M Schwartz; Kenneth P Parsley; Daniel S Zahm
Journal:  Brain Struct Funct       Date:  2018-04-26       Impact factor: 3.270

3.  Sources of input to the rostromedial tegmental nucleus, ventral tegmental area, and lateral habenula compared: A study in rat.

Authors:  Leora Yetnikoff; Anita Y Cheng; Heather N Lavezzi; Kenneth P Parsley; Daniel S Zahm
Journal:  J Comp Neurol       Date:  2015-06-10       Impact factor: 3.215

4.  Dissociable effects of dopamine D1 and D2 receptors on compulsive ingestion and pivoting movements elicited by disinhibiting the ventral pallidum.

Authors:  Rhett A Reichard; Kenneth P Parsley; Suriya Subramanian; Daniel S Zahm
Journal:  Brain Struct Funct       Date:  2019-05-13       Impact factor: 3.270

5.  Evaluation of the interaction of mu and kappa opioid agonists on locomotor behavior in the horse.

Authors:  K R Mama; P J Pascoe; E P Steffey
Journal:  Can J Vet Res       Date:  1993-04       Impact factor: 1.310

6.  Comparison of the locomotor-activating effects of bicuculline infusions into the preoptic area and ventral pallidum.

Authors:  Daniel S Zahm; Zachary M Schwartz; Heather N Lavezzi; Leora Yetnikoff; Kenneth P Parsley
Journal:  Brain Struct Funct       Date:  2013-02-20       Impact factor: 3.270

7.  Dopamine Regulation of Lateral Inhibition between Striatal Neurons Gates the Stimulant Actions of Cocaine.

Authors:  Lauren K Dobbs; Alanna R Kaplan; Julia C Lemos; Aya Matsui; Marcelo Rubinstein; Veronica A Alvarez
Journal:  Neuron       Date:  2016-05-12       Impact factor: 17.173

8.  Cocaine and amphetamine-regulated transcript-containing neurons in the nucleus accumbens project to the ventral pallidum in the rat and may inhibit cocaine-induced locomotion.

Authors:  G W Hubert; D F Manvich; M J Kuhar
Journal:  Neuroscience       Date:  2009-10-12       Impact factor: 3.590

9.  Modulation of locomotor activation by the rostromedial tegmental nucleus.

Authors:  Heather N Lavezzi; Kenneth P Parsley; Daniel S Zahm
Journal:  Neuropsychopharmacology       Date:  2014-08-28       Impact factor: 7.853

10.  Dopamine depletion reorganizes projections from the nucleus accumbens and ventral pallidum that mediate opioid-induced motor activity.

Authors:  L Churchill; M A Klitenick; P W Kalivas
Journal:  J Neurosci       Date:  1998-10-01       Impact factor: 6.167
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