Literature DB >> 27789523

Zika virus NS1, a pathogenicity factor with many faces.

Rolf Hilgenfeld1,2.   

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Year:  2016        PMID: 27789523      PMCID: PMC5167348          DOI: 10.15252/embj.201695871

Source DB:  PubMed          Journal:  EMBO J        ISSN: 0261-4189            Impact factor:   11.598


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  13 in total

1.  Secreted dengue virus nonstructural protein NS1 is an atypical barrel-shaped high-density lipoprotein.

Authors:  Irina Gutsche; Fasséli Coulibaly; James E Voss; Jérôme Salmon; Jacques d'Alayer; Myriam Ermonval; Eric Larquet; Pierre Charneau; Thomas Krey; Françoise Mégret; Eric Guittet; Félix A Rey; Marie Flamand
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-25       Impact factor: 11.205

Review 2.  The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker.

Authors:  David A Muller; Paul R Young
Journal:  Antiviral Res       Date:  2013-03-21       Impact factor: 5.970

3.  Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system.

Authors:  David L Akey; W Clay Brown; Somnath Dutta; Jamie Konwerski; Joyce Jose; Thomas J Jurkiw; James DelProposto; Craig M Ogata; Georgios Skiniotis; Richard J Kuhn; Janet L Smith
Journal:  Science       Date:  2014-02-06       Impact factor: 47.728

4.  Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection.

Authors:  Karin Stettler; Martina Beltramello; Diego A Espinosa; Victoria Graham; Antonino Cassotta; Siro Bianchi; Fabrizia Vanzetta; Andrea Minola; Stefano Jaconi; Federico Mele; Mathilde Foglierini; Mattia Pedotti; Luca Simonelli; Stuart Dowall; Barry Atkinson; Elena Percivalle; Cameron P Simmons; Luca Varani; Johannes Blum; Fausto Baldanti; Elisabetta Cameroni; Roger Hewson; Eva Harris; Antonio Lanzavecchia; Federica Sallusto; Davide Corti
Journal:  Science       Date:  2016-07-14       Impact factor: 47.728

Review 5.  The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design.

Authors:  Daniel Watterson; Naphak Modhiran; Paul R Young
Journal:  Antiviral Res       Date:  2016-03-02       Impact factor: 5.970

6.  Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity.

Authors:  Naphak Modhiran; Daniel Watterson; David A Muller; Adele K Panetta; David P Sester; Lidong Liu; David A Hume; Katryn J Stacey; Paul R Young
Journal:  Sci Transl Med       Date:  2015-09-09       Impact factor: 17.956

7.  Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination.

Authors:  P Robert Beatty; Henry Puerta-Guardo; Sarah S Killingbeck; Dustin R Glasner; Kaycie Hopkins; Eva Harris
Journal:  Sci Transl Med       Date:  2015-09-09       Impact factor: 17.956

8.  Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus.

Authors:  Soonjeon Youn; Tuo Li; Broc T McCune; Melissa A Edeling; Daved H Fremont; Ileana M Cristea; Michael S Diamond
Journal:  J Virol       Date:  2012-05-02       Impact factor: 5.103

9.  High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses.

Authors:  Daniela Huzly; Ingeborg Hanselmann; Jonas Schmidt-Chanasit; Marcus Panning
Journal:  Euro Surveill       Date:  2016-04-21

10.  Contribution of intertwined loop to membrane association revealed by Zika virus full-length NS1 structure.

Authors:  Xiaoying Xu; Hao Song; Jianxun Qi; Yuqian Liu; Haiyuan Wang; Chao Su; Yi Shi; George F Gao
Journal:  EMBO J       Date:  2016-08-30       Impact factor: 11.598

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  14 in total

1.  Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis.

Authors:  Yanyan Zheng; Qingxiang Liu; Yaoxing Wu; Ling Ma; Zhenzhen Zhang; Tao Liu; Shouheng Jin; Yuanchu She; Yi-Ping Li; Jun Cui
Journal:  EMBO J       Date:  2018-07-31       Impact factor: 11.598

2.  Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models.

Authors:  Penghui Li; Xianliang Ke; Ting Wang; Zhongyuan Tan; Dan Luo; Yuanjiu Miao; Jianhong Sun; Yuan Zhang; Yan Liu; Qinxue Hu; Fuqiang Xu; Hanzhong Wang; Zhenhua Zheng
Journal:  J Virol       Date:  2018-08-16       Impact factor: 5.103

3.  Generation of Zika virus-specific T cells from seropositive and virus-naïve donors for potential use as an autologous or "off-the-shelf" immunotherapeutic.

Authors:  Ryo Hanajiri; Gelina M Sani; Patrick J Hanley; Cassia G Silveira; Esper G Kallas; Michael D Keller; Catherine M Bollard
Journal:  Cytotherapy       Date:  2019-07-04       Impact factor: 5.414

4.  Zika Virus NS1 Suppresses VE-Cadherin and Claudin-5 via hsa-miR-101-3p in Human Brain Microvascular Endothelial Cells.

Authors:  Utkarsh Bhardwaj; Sunit K Singh
Journal:  Mol Neurobiol       Date:  2021-09-06       Impact factor: 5.590

5.  Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract.

Authors:  Drishya Kurup; Christoph Wirblich; Rachael Lambert; Leila Zabihi Diba; Benjamin E Leiby; Matthias J Schnell
Journal:  NPJ Vaccines       Date:  2022-04-19       Impact factor: 9.399

Review 6.  Zika Virus Vaccines: Challenges and Perspectives.

Authors:  Raquel das Neves Almeida; Trina Racine; Kelly G Magalhães; Gary P Kobinger
Journal:  Vaccines (Basel)       Date:  2018-09-13

7.  Attenuation of Zika Virus by Passage in Human HeLa Cells.

Authors:  Li Li; Natalie D Collins; Steven G Widen; Emily H Davis; Jaclyn A Kaiser; Mellodee M White; M Banks Greenberg; Alan D T Barrett; Nigel Bourne; Vanessa V Sarathy
Journal:  Vaccines (Basel)       Date:  2019-08-20

8.  CpG-Recoding in Zika Virus Genome Causes Host-Age-Dependent Attenuation of Infection With Protection Against Lethal Heterologous Challenge in Mice.

Authors:  Ivan Trus; Daniel Udenze; Nathalie Berube; Colette Wheler; Marie-Jocelyne Martel; Volker Gerdts; Uladzimir Karniychuk
Journal:  Front Immunol       Date:  2020-01-24       Impact factor: 7.561

9.  Delayed and highly specific antibody response to nonstructural protein 1 (NS1) revealed during natural human ZIKV infection by NS1-based capture ELISA.

Authors:  Xiujie Gao; Yingfen Wen; Jian Wang; Wenxin Hong; Chunlin Li; Lingzhai Zhao; Chibiao Yin; Xia Jin; Fuchun Zhang; Lei Yu
Journal:  BMC Infect Dis       Date:  2018-06-14       Impact factor: 3.090

10.  An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection against Lethal Challenge in a Mouse Model.

Authors:  Arun S Annamalai; Aryamav Pattnaik; Bikash R Sahoo; Zack P Guinn; Brianna L Bullard; Eric A Weaver; David Steffen; Sathish Kumar Natarajan; Thomas M Petro; Asit K Pattnaik
Journal:  Vaccines (Basel)       Date:  2019-09-12
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