Literature DB >> 27789406

Characterization of dermal fibroblast-derived iPSCs from a patient with low grade steatosis.

Marie-Ann Kawala1, Martina Bohndorf1, Nina Graffmann1, Wasco Wruck1, Kurt Zatloukal2, James Adjaye3.   

Abstract

Primary fibroblasts from a low grade steatosis patient were reprogrammed by transduction of a combination of two episomal-based plasmids OCT4,SOX2, c-MYC and KLF4. iPSCs were characterized by immunocytochemistry, embryonic body-formation, DNA-fingerprint karyotype analysis and comparative transcriptome analyses with the human embryonic stem cell line H1 revealed a Pearsons correlation of 0.9251.
Copyright © 2016 Michael Boutros, German Cancer Research Center, Heidelberg, Germany. Published by Elsevier B.V. All rights reserved.

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Year:  2016        PMID： 27789406     DOI： 10.1016/j.scr.2016.10.004

Source DB:  PubMed          Journal:  Stem Cell Res        ISSN： 1873-5061            Impact factor:   2.020


  2 in total

1.  Episomal Induced Pluripotent Stem Cells: Functional and Potential Therapeutic Applications.

Authors:  Aline Yen Ling Wang; Charles Yuen Yung Loh
Journal:  Cell Transplant       Date:  2019-11-14       Impact factor: 4.064

2.  A stem cell based in vitro model of NAFLD enables the analysis of patient specific individual metabolic adaptations in response to a high fat diet and AdipoRon interference.

Authors:  Nina Graffmann; Audrey Ncube; Soraia Martins; Aurelian Robert Fiszl; Philipp Reuther; Martina Bohndorf; Wasco Wruck; Mathias Beller; Constantin Czekelius; James Adjaye
Journal:  Biol Open       Date:  2021-01-25       Impact factor: 2.643
  2 in total

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