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Literature DB >> 27789397

Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions.

Malin Kele¹, Kelly Day¹, Harriet Rönnholm¹, Jens Schuster², Niklas Dahl², Anna Falk³.

Abstract

CTL07-II is a healthy feeder-free and characterized human induced pluripotent stem (iPS) cell line. Cultured under xeno-free and defined conditions. The line is generated from healthy human fibroblasts with non-integrating Sendai virus vectors encoding the four Yamanaka factors, OCT4, SOX2, KLF4 and cMYC. The generated iPS cells are free from reprogramming vectors and their purity, karyotypic stability and pluripotent capacity is confirmed.

Entities: CellLine Species

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Year: 2016 PMID： 27789397 DOI： 10.1016/j.scr.2016.09.028

Source DB: PubMed Journal: Stem Cell Res ISSN： 1873-5061 Impact factor: 2.020

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Cited

6 in total

1. Integration Free Derivation of Human Induced Pluripotent Stem Cells Using Laminin 521 Matrix.

Authors: Elias Uhlin; Ana Marin Navarro; Harriet Rönnholm; Kelly Day; Malin Kele; Anna Falk
Journal: J Vis Exp Date: 2017-07-07 Impact factor: 1.355

2. Mutations in the mitochondrial tryptophanyl-tRNA synthetase cause growth retardation and progressive leukoencephalopathy.

Authors: Camilla Maffezzini; Isabelle Laine; Cristina Dallabona; Paula Clemente; Javier Calvo-Garrido; Rolf Wibom; Karin Naess; Michela Barbaro; Anna Falk; Claudia Donnini; Christoph Freyer; Anna Wredenberg; Anna Wedell
Journal: Mol Genet Genomic Med Date: 2019-03-28 Impact factor: 2.183

3. Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186.

Authors: Malin Kvarnung; Mansoureh Shahsavani; Fulya Taylan; Mohsen Moslem; Nicole Breeuwsma; Loora Laan; Jens Schuster; Zhe Jin; Daniel Nilsson; Agne Lieden; Britt-Marie Anderlid; Magnus Nordenskjöld; Elisabeth Syk Lundberg; Bryndis Birnir; Niklas Dahl; Ann Nordgren; Anna Lindstrand; Anna Falk
Journal: Front Genet Date: 2019-09-24 Impact factor: 4.599

Generation of human iPS cell line CTL07-II from human fibroblasts, under defined and xeno-free conditions.

1. Integration Free Derivation of Human Induced Pluripotent Stem Cells Using Laminin 521 Matrix.

2. Mutations in the mitochondrial tryptophanyl-tRNA synthetase cause growth retardation and progressive leukoencephalopathy.

3. Ataxia in Patients With Bi-Allelic NFASC Mutations and Absence of Full-Length NF186.

4. Partial Monosomy 21 Mirrors Gene Expression of Trisomy 21 in a Patient-Derived Neuroepithelial Stem Cell Model.

5. Generation of Human iPSC-Derived Astrocytes with a mature star-shaped phenotype for CNS modeling.

6. Engineered Human Induced Pluripotent Cells Enable Genetic Code Expansion in Brain Organoids.