Literature DB >> 27789250

Enrolling African-American and Latino patients with asthma in comparative effectiveness research: Lessons learned from 8 patient-centered studies.

C Bradley Kramer1, Lisa LeRoy2, Sara Donahue2, Andrea J Apter3, Tyra Bryant-Stephens4, John P Elder5, Winifred J Hamilton6, Jerry A Krishnan7, Deborah Q Shelef8, James W Stout9, Kaharu Sumino10, Stephen J Teach11, Alex D Federman12.   

Abstract

BACKGROUND: African-American and Latino patients are often difficult to recruit for asthma studies. This challenge is a barrier to improving asthma care and outcomes for these populations.
OBJECTIVES: We sought to examine the recruitment experiences of 8 asthma comparative effectiveness studies that specifically targeted African-American and Latino patients, and identify the solutions they developed to improve recruitment.
METHODS: Case report methodology was used to gather and evaluate information on study design, recruitment procedures and outcomes from study protocols and annual reports, and in-depth interviews with each research team. Data were analyzed for themes, commonalities, and differences.
RESULTS: There were 4 domains of recruitment challenges: individual participant, institutional, research team, and study intervention. Participants had competing demands for time and some did not believe they had asthma. Institutional challenges included organizational policies governing monetary incentives and staff hiring. Research team challenges included ongoing training needs of recruitment staff, and intervention designs often were unappealing to participants because of inconveniences. Teams identified a host of strategies to address these challenges, most importantly engagement of patients and other stakeholders in study design and troubleshooting, and flexibility in data collection and intervention application to meet the varied needs of patients.
CONCLUSIONS: Asthma researchers may have greater success with recruitment by addressing uncertainty among patients about asthma diagnosis, engaging stakeholders in all aspects of study design and implementation, and maximizing flexibility of study and intervention protocols. However, even with such efforts, engagement of African-American and Latino patients in asthma research may remain low. Greater investment in research on engaging these populations in asthma research may ultimately be needed to improve their asthma care and outcomes. Copyright Â
© 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Comparative effectiveness research; asthma; patient-centered outcomes research; study recruitment; vulnerable populations

Mesh:

Year:  2016        PMID: 27789250     DOI: 10.1016/j.jaci.2016.10.011

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  8 in total

Review 1.  Managing Asthma in Low-Income, Underrepresented Minority, and Other Disadvantaged Pediatric Populations: Closing the Gap.

Authors:  Margee Louisias; Wanda Phipatanakul
Journal:  Curr Allergy Asthma Rep       Date:  2017-09-15       Impact factor: 4.806

2.  Racial/ethnic concordance between patients and researchers as a predictor of study attrition.

Authors:  Irina Mindlis; David Livert; Alex D Federman; Juan P Wisnivesky; Tracey A Revenson
Journal:  Soc Sci Med       Date:  2020-04-22       Impact factor: 4.634

3.  Strategies for recruitment and retention of underrepresented populations with chronic obstructive pulmonary disease for a clinical trial.

Authors:  Beatrice Huang; Denise De Vore; Chris Chirinos; Jessica Wolf; Devon Low; Rachel Willard-Grace; Stephanie Tsao; Chris Garvey; Doranne Donesky; George Su; David H Thom
Journal:  BMC Med Res Methodol       Date:  2019-02-21       Impact factor: 4.615

4.  Health Literacy and Income Mediate Racial/Ethnic Asthma Disparities.

Authors:  Ryan G Seibert; Michael R Winter; Howard J Cabral; Michael S Wolf; Laura M Curtis; Michael K Paasche-Orlow
Journal:  Health Lit Res Pract       Date:  2019-01-18

Review 5.  Burden of allergic disease among ethnic minority groups in high-income countries.

Authors:  Christina J Jones; Priyamvada Paudyal; Robert M West; Adel H Mansur; Nicola Jay; Nick Makwana; Sarah Baker; Mamidipudi T Krishna
Journal:  Clin Exp Allergy       Date:  2022-04-14       Impact factor: 5.401

6.  Recruiting Participants in Vulnerable Situations: A Qualitative Evaluation of the Recruitment Process in the EFFICHRONIC Study.

Authors:  Pilar Serrano-Gallardo; Viola Cassetti; An L D Boone; Marta María Pisano-González
Journal:  Int J Environ Res Public Health       Date:  2022-08-29       Impact factor: 4.614

Review 7.  An Overview of Health Disparities in Asthma.

Authors:  Mario F Perez; Maria Teresa Coutinho
Journal:  Yale J Biol Med       Date:  2021-09-30

8.  Enhancing Recruitment and Retention of Minority Populations for Clinical Research in Pulmonary, Critical Care, and Sleep Medicine: An Official American Thoracic Society Research Statement.

Authors:  Neeta Thakur; Stephanie Lovinsky-Desir; Donna Appell; Christian Bime; Lauren Castro; Juan C Celedón; Juliana Ferreira; Maureen George; Yolanda Mageto; Arch G Mainous III; Smita Pakhale; Kristin A Riekert; Jesse Roman; Elizabeth Ruvalcaba; Sunil Sharma; Priya Shete; Juan P Wisnivesky; Fernando Holguin
Journal:  Am J Respir Crit Care Med       Date:  2021-08-01       Impact factor: 21.405

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.