Literature DB >> 2778667

Acid catalyzed hydrolysis of a series of zopiclone analogues.

M Largeron1, M B Fleury.   

Abstract

The pKa values of acid-base equilibria involved in the protonation of zopiclone and analogues are determined by UV-visible absorption spectrometry and pH-metry. Hydrogen ion catalysis is evidenced in the carbamate hydrolysis.

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Year:  1989        PMID: 2778667     DOI: 10.1002/jps.2600780805

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Degradation of zopiclone during storage of spiked and authentic whole blood and matching dried blood spots.

Authors:  Ricarda Jantos; Annemiek Vermeeren; Danica Sabljic; Johannes G Ramaekers; Gisela Skopp
Journal:  Int J Legal Med       Date:  2012-04-25       Impact factor: 2.686

  1 in total

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