Literature DB >> 27785808

A model of BCR-FGFR1 driven human AML in immunocompromised mice.

John K Cowell1, Haiyan Qin2, Chang-Sheng Chang2, Eiko Kitamura2, Mingqiang Ren3.   

Abstract

Entities:  

Keywords:  BCR-FGFR1; HSC; NSG mice; acute myeloid leukaemia

Mesh：

Substances：

Year:  2015        PMID： 27785808      PMCID： PMC5609710          DOI： 10.1111/bjh.13877

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


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  10 in total

1.  B-cell acute lymphoblastic leukemia as evolution of a 8p11 myeloproliferative syndrome with t(8;22)(p11;q11) and BCR-FGFR1 fusion gene.

Authors:  Carmen Baldazzi; Ilaria Iacobucci; Simona Luatti; Emanuela Ottaviani; Giulia Marzocchi; Stefania Paolini; Monica Stacchini; Cristina Papayannidis; Carla Gamberini; Giovanni Martinelli; Michele Baccarani; Nicoletta Testoni
Journal:  Leuk Res       Date:  2010-06-09       Impact factor: 3.156

2.  FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33).

Authors:  G Guasch; G J Mack; C Popovici; N Dastugue; D Birnbaum; J B Rattner; M J Pébusque
Journal:  Blood       Date:  2000-03-01       Impact factor: 22.113

3.  The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins.

Authors:  A Demiroglu; E J Steer; C Heath; K Taylor; M Bentley; S L Allen; P Koduru; J P Brody; G Hawson; R Rodwell; M L Doody; F Carnicero; A Reiter; J M Goldman; J V Melo; N C Cross
Journal:  Blood       Date:  2001-12-15       Impact factor: 22.113

Review 4.  8p11 myeloproliferative syndrome: a review.

Authors:  Courtney C Jackson; L Jeffrey Medeiros; Roberto N Miranda
Journal:  Hum Pathol       Date:  2010-04       Impact factor: 3.466

5.  Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.

Authors:  Helena Agerstam; Marcus Järås; Anna Andersson; Petra Johnels; Nils Hansen; Carin Lassen; Marianne Rissler; David Gisselsson; Tor Olofsson; Johan Richter; Xiaolong Fan; Mats Ehinger; Thoas Fioretos
Journal:  Blood       Date:  2010-06-16       Impact factor: 22.113

6.  The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors.

Authors:  Heinz Baumann; Padmaja Kunapuli; Erin Tracy; John K Cowell
Journal:  J Biol Chem       Date:  2003-02-19       Impact factor: 5.157

7.  Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.

Authors:  Mingqiang Ren; Haiyan Qin; Eiko Kitamura; John K Cowell
Journal:  Blood       Date:  2013-06-18       Impact factor: 22.113

8.  Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations.

Authors:  Sergei Roumiantsev; Daniela S Krause; Carola A Neumann; Christopher A Dimitri; Frances Asiedu; Nicholas C P Cross; Richard A Van Etten
Journal:  Cancer Cell       Date:  2004-03       Impact factor: 31.743

9.  Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.

Authors:  Mingqiang Ren; Xiurong Li; John K Cowell
Journal:  Blood       Date:  2009-06-08       Impact factor: 22.113

10.  Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage.

Authors:  Mingqiang Ren; Josephine A Tidwell; Suash Sharma; John K Cowell
Journal:  PLoS One       Date:  2012-06-06       Impact factor: 3.240
  10 in total
  8 in total

1.  miR-339 Promotes Development of Stem Cell Leukemia/Lymphoma Syndrome via Downregulation of the BCL2L11 and BAX Proapoptotic Genes.

Authors:  Tianxiang Hu; Yating Chong; Sumin Lu; Rebecca Wang; Haiyan Qin; Jeane Silva; Eiko Kitamura; Chang-Sheng Chang; LesleyAnn Hawthorn; John K Cowell
Journal:  Cancer Res       Date:  2018-05-07       Impact factor: 12.701

2.  Loss of the BCR-FGFR1 GEF Domain Suppresses RHOA Activation and Enhances B-Lymphomagenesis in Mice.

Authors:  Tianxiang Hu; Yating Chong; Sumin Lu; Haiyan Qin; Mingqiang Ren; Natasha M Savage; Chang-Sheng Chang; John K Cowell
Journal:  Cancer Res       Date:  2018-11-09       Impact factor: 12.701

3.  Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas.

Authors:  John K Cowell; Haiyan Qin; Tianxiang Hu; Qing Wu; Aaron Bhole; Mingqiang Ren
Journal:  Int J Cancer       Date:  2017-07-28       Impact factor: 7.396

4.  The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase.

Authors:  Tianxiang Hu; Yating Chong; Haiyan Qin; Eiko Kitamura; Chang-Sheng Chang; Jeane Silva; Mingqiang Ren; John K Cowell
Journal:  Oncogene       Date:  2018-01-25       Impact factor: 9.867

5.  Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway.

Authors:  Xuehong Zhang; Furong Wang; Fanzhi Yan; Dan Huang; Haina Wang; Beibei Gao; Yuan Gao; Zhijie Hou; Jiacheng Lou; Weiling Li; Jinsong Yan
Journal:  Cancer Cell Int       Date:  2022-01-26       Impact factor: 5.722

6.  IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies.

Authors:  Baohuan Cai; Yun Liu; Yating Chong; Hualei Zhang; Atsuko Matsunaga; Xuexiu Fang; Rafal Pacholczyk; Gang Zhou; John K Cowell; Tianxiang Hu
Journal:  Mol Cancer       Date:  2021-12-14       Impact factor: 27.401

7.  FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome.

Authors:  Tianxiang Hu; Qing Wu; Yating Chong; Haiyan Qin; Candace J Poole; Jan van Riggelen; Mingqiang Ren; John K Cowell
Journal:  Leukemia       Date:  2018-04-02       Impact factor: 11.528

8.  Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome.

Authors:  Yun Liu; Baohuan Cai; Yating Chong; Hualei Zhang; Chesley-Anne Kemp; Sumin Lu; Chang-Sheng Chang; Mingqiang Ren; John K Cowell; Tianxiang Hu
Journal:  Cell Death Dis       Date:  2020-10-20       Impact factor: 8.469
  8 in total

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