Cemile Ayşe Görmeli1, Zeynep Maraş Özdemir2, Ayşegül Sağır Kahraman2, Jülide Yağmur3, Ramazan Özdemir3, Cemil Çolak4. 1. Department of Radiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Radyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey. ayseyazici@yahoo.com. 2. Department of Radiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Radyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey. 3. Department of Cardiology, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Kardiyoloji Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey. 4. Department of Biostatistics, Inonu University School of Medicine, İnönü Üniversitesi Turgut Özal Tıp Merkezi Biyoistatistik Ana Bilimdali, Elazığ yolu 15. km, Merkez, Malatya, 44000, Turkey.
Abstract
PURPOSE: The aim of this study was to examine the correlation between ventricular function and the extracellular volume fraction (ECV) in patients with non-ischemic dilated cardiomyopathy (NIDCM) using 3.0 T magnetic resonance imaging (MRI). We also hypothesized that native T1 and ECV values would be increased in patients with NIDCM, independent of the left ventricular ejection fraction (LVEF). The findings of our study could lead to further studies of the follow-up protocols. MATERIALS AND METHODS: In total, 53 consecutive dilated cardiomyopathy patients who had undergone cardiac MRI were functionally evaluated and underwent tissue characterization. RESULTS: The mean native T1 value was 1235 ± 10 ms, and the mean ECV value was 35.4 ± 2.7% in the myocardia. The LVEF values ranged from 29 to 44%. No significant correlations were observed between functional analysis measurements and native T1 or ECV values. CONCLUSIONS: Our results showed that myocardial fibrosis is unrelated to cardiac functional findings in NIDCM patients. Therefore, we propose that these patients should be evaluated using MRI and tissue characterization techniques, in addition to cardiac functional analysis.
PURPOSE: The aim of this study was to examine the correlation between ventricular function and the extracellular volume fraction (ECV) in patients with non-ischemic dilated cardiomyopathy (NIDCM) using 3.0 T magnetic resonance imaging (MRI). We also hypothesized that native T1 and ECV values would be increased in patients with NIDCM, independent of the left ventricular ejection fraction (LVEF). The findings of our study could lead to further studies of the follow-up protocols. MATERIALS AND METHODS: In total, 53 consecutive dilated cardiomyopathypatients who had undergone cardiac MRI were functionally evaluated and underwent tissue characterization. RESULTS: The mean native T1 value was 1235 ± 10 ms, and the mean ECV value was 35.4 ± 2.7% in the myocardia. The LVEF values ranged from 29 to 44%. No significant correlations were observed between functional analysis measurements and native T1 or ECV values. CONCLUSIONS: Our results showed that myocardial fibrosis is unrelated to cardiac functional findings in NIDCMpatients. Therefore, we propose that these patients should be evaluated using MRI and tissue characterization techniques, in addition to cardiac functional analysis.
Entities:
Keywords:
Cardiac magnetic resonance imaging; Extracellular volume fraction; Left ventricular ejection fraction; Myocardial fibrosis; Nonischemic dilated cardiomyopathy; T1 mapping
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