Literature DB >> 27785535

[Conversion of sound into auditory nerve action potentials].

J Encke1, J Kreh1, F Völk1, W Hemmert2.   

Abstract

Outer hair cells play a major role in the hearing process: they amplify the motion of the basilar membrane up to a 1000-fold and at the same time sharpen the excitation patterns. These patterns are converted by inner hair cells into action potentials of the auditory nerve. Outer hair cells are delicate structures and easily damaged, e. g., by overexposure to noise. Hearing aids can amplify the amplitude of the excitation patterns, but they cannot restore their degraded frequency selectivity. Noise overexposure also leads to delayed degeneration of auditory nerve fibers, particularly those with low a spontaneous rate, which are important for the coding of sound in noise. However, this loss cannot be diagnosed by pure-tone audiometry.

Entities:  

Keywords:  Auditory perception; Cochlear hair cells; Computer models; Hearing loss; Inner ear

Mesh:

Year:  2016        PMID: 27785535     DOI: 10.1007/s00106-016-0258-z

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  24 in total

1.  Three-dimensional motion of the organ of Corti.

Authors:  W Hemmert; H P Zenner; A W Gummer
Journal:  Biophys J       Date:  2000-05       Impact factor: 4.033

2.  Limiting dynamics of high-frequency electromechanical transduction of outer hair cells.

Authors:  G Frank; W Hemmert; A W Gummer
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-13       Impact factor: 11.205

3.  Membrane potential and ion channels in isolated outer hair cells of guinea pig cochlea.

Authors:  A H Gitter; H P Zenner; E Frömter
Journal:  ORL J Otorhinolaryngol Relat Spec       Date:  1986       Impact factor: 1.538

4.  Longitudinally propagating traveling waves of the mammalian tectorial membrane.

Authors:  Roozbeh Ghaffari; Alexander J Aranyosi; Dennis M Freeman
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-09       Impact factor: 11.205

5.  Prestin is the motor protein of cochlear outer hair cells.

Authors:  J Zheng; W Shen; D Z He; K B Long; L D Madison; P Dallos
Journal:  Nature       Date:  2000-05-11       Impact factor: 49.962

Review 6.  The role of fluid inertia in mechanical stimulation of hair cells.

Authors:  D M Freeman; T F Weiss
Journal:  Hear Res       Date:  1988-09-15       Impact factor: 3.208

7.  [Laser vibrometry. A middle ear and cochlear analyzer for noninvasive studies of middle and inner ear function disorders].

Authors:  J Rodriguez Jorge; H P Zenner; W Hemmert; C Burkhardt; A W Gummer
Journal:  HNO       Date:  1997-12       Impact factor: 1.284

8.  Evoked mechanical responses of isolated cochlear outer hair cells.

Authors:  W E Brownell; C R Bader; D Bertrand; Y de Ribaupierre
Journal:  Science       Date:  1985-01-11       Impact factor: 47.728

9.  The responses of inner hair cells to basilar membrane velocity during low frequency auditory stimulation in the guinea pig cochlea.

Authors:  P M Sellick; I J Russell
Journal:  Hear Res       Date:  1980-06       Impact factor: 3.208

10.  Sharp Ca²⁺ nanodomains beneath the ribbon promote highly synchronous multivesicular release at hair cell synapses.

Authors:  Cole W Graydon; Soyoun Cho; Geng-Lin Li; Bechara Kachar; Henrique von Gersdorff
Journal:  J Neurosci       Date:  2011-11-16       Impact factor: 6.167

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