Literature DB >> 27785286

Hypervascular Lesion in a Cirrhotic Liver: A Case Report.

Lucas Carvalho Santos1, Juliana Bianchi1, Suzzanna Ingryd Goncalves Souza1, Luiz Arnaldo Szutan2.   

Abstract

Hepatocellular carcinoma (HCC) is the leading cause of death among patients with cirrhosis. Therefore, a focal hepatic lesion in a patient with cirrhosis must always be investigated for its high risk of cancer. However, when hepatic lesions in an imaging exam do not present the typical characteristics of a malignant or a benignant tumor, diagnosis may be a challenge. The biopsy can be used in these circumstances, but, as shown by this case, even that can be misleading. A 54-year-old male patient with cirrhosis presented with abdominal pain, jaundice, nausea and vomits. He performed a biopsy at another service, with the result being focal nodular hyperplasia (FNH). He presented adequate hepatic function, and alpha-fetoprotein level was 6.4. Upon first consultation, we required the slides to be brought to our service and reviewed. Our revision also showed no signs of malignancy. Magnetic resonance imaging showed a large hepatic tumor in segments V and VI, predominantly exofitic, with a central scar. The tumor was surgically removed, and its dimensions were 14 × 10 × 9 cm. Microscopic examination revealed an HCC. Even though histological diagnosis was not necessary to indicate surgery, due to its exofitic nature and adequate hepatic function, we discuss the diagnostic characteristics of both HCC and FNH that could help other medical groups in cases where the position of a liver tumor could make the decision to operate more difficult.

Entities:  

Keywords:  Focal nodular hyperplasia; Hepatocellular carcinoma; Hypervascular lesion; Liver

Year:  2014        PMID: 27785286      PMCID: PMC5040539          DOI: 10.14740/gr630w

Source DB:  PubMed          Journal:  Gastroenterology Res        ISSN: 1918-2805


  5 in total

Review 1.  Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis.

Authors:  Shahid M Hussain; Türkan Terkivatan; Pieter E Zondervan; Esmée Lanjouw; Sjoerd de Rave; Jan N M Ijzermans; Rob A de Man
Journal:  Radiographics       Date:  2004 Jan-Feb       Impact factor: 5.333

Review 2.  Current management of hepatocellular carcinoma.

Authors:  Parissa Tabrizian; Sasan Roayaie; Myron E Schwartz
Journal:  World J Gastroenterol       Date:  2014-08-14       Impact factor: 5.742

3.  Focal nodular hyperplasia of the liver in 86 patients.

Authors:  Ying-Hao Shen; Jia Fan; Zhi-Quan Wu; Zeng-Chen Ma; Xin-Da Zhou; Jian Zhou; Shuang-Jian Qiu; Lun-Xiu Qin; Qin-Hai Ye; Hui-Chuan Sun; Xiao-Wu Huang; Zhao-You Tang
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2007-02

4.  MRI in detection of hepatocellular carcinoma (HCC).

Authors:  Subba R Digumarthy; Dushyant V Sahani; Sanjay Saini
Journal:  Cancer Imaging       Date:  2005-04-13       Impact factor: 3.909

Review 5.  Hypervascular benign and malignant liver tumors that require differentiation from hepatocellular carcinoma: key points of imaging diagnosis.

Authors:  Takamichi Murakami; Masakatsu Tsurusaki
Journal:  Liver Cancer       Date:  2014-05       Impact factor: 11.740

  5 in total

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