| Literature DB >> 2778493 |
T Kobayashi1, T Tanaka, Y Kida, M Matsui, T Ikeda.
Abstract
New experimental system of induction hyperthermia for brain tumor using ferromagnetic implant with low Curie point has been developed. The metal implant is cylindrical needle and made of Fe-Pt alloy with low Curie point suitable for hyperthermia (50-60 degrees C). Induction coil and generator which produce maximum power of 200W and variable frequency of 100-500kHz, yielding magnetic power of 16.7Oe, have been developed. Interstitial hyperthermia was made on rat brain tumor model (T9 gliosarcoma) by this system. Significant effects of single hyperthermia (45 degrees C for 30 minutes) were observed by the extension of life span and morphological changes of the tumor.Entities:
Mesh:
Year: 1989 PMID: 2778493 DOI: 10.1007/BF00165105
Source DB: PubMed Journal: J Neurooncol ISSN: 0167-594X Impact factor: 4.130