Literature DB >> 27783218

Helicobacter pylori-negative gastric cancer: advanced-stage undifferentiated adenocarcinoma located in the pyloric gland area.

Akihiro Okano1, Shigeru Kato2, Masaya Ohana3.   

Abstract

The incidence of Helicobacter pylori-negative gastric cancer (HpNGC) is extremely low. A 78-year old female without H. pylori infection was diagnosed with type 4 advanced-stage gastric prepylorus cancer. Distal gastrectomy was performed as for HpNGC (cT3N0M0). Histological findings of the resected specimen showed poorly differentiated adenocarcinoma and signet ring cell carcinoma, which were located in the pyloric gland area, diffusely invaded beyond the serosa without lymph node metastasis (pT4aN0M0). Most cases of undifferentiated-type HpNGC are diagnosed in the early stage and are located in the fundic gland area. We report the first case of advanced-stage undifferentiated HpNGC located in the pyloric gland area.

Entities:  

Keywords:  Advanced stage; Gastric cancer; Helicobacter pylori-negative; Pyloric gland; Undifferentiated adenocarcinoma

Mesh：

Year:  2016        PMID： 27783218     DOI： 10.1007/s12328-016-0696-x

Source DB:  PubMed          Journal:  Clin J Gastroenterol        ISSN： 1865-7265


  21 in total

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2.  Low prevalence of Helicobacter pylori-negative gastric cancer among Japanese.

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Journal:  Helicobacter       Date:  2011-12       Impact factor: 5.753

3.  Helicobacter pylori-negative gastric cancer in South Korea: incidence and clinicopathologic characteristics.

Authors:  Hyuk Yoon; Nayoung Kim; Hye Seung Lee; Cheol Min Shin; Young Soo Park; Dong Ho Lee; Hyun Chae Jung; In Sung Song
Journal:  Helicobacter       Date:  2011-10       Impact factor: 5.753

4.  E-cadherin germline mutations in familial gastric cancer.

Authors:  P Guilford; J Hopkins; J Harraway; M McLeod; N McLeod; P Harawira; H Taite; R Scoular; A Miller; A E Reeve
Journal:  Nature       Date:  1998-03-26       Impact factor: 49.962

5.  Gastric adenocarcinoma of fundic gland type (chief cell predominant type): proposal for a new entity of gastric adenocarcinoma.

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6.  Biological behavior of the intramucosal Helicobacter pylori-negative undifferentiated-type early gastric cancer: comparison with Helicobacter pylori-positive early gastric cancer.

Authors:  Yusuke Horiuchi; Junko Fujisaki; Noriko Yamamoto; Tomoki Shimizu; Yuji Miyamoto; Hideomi Tomida; Chika Taniguchi; Kenjiro Morishige; Masami Omae; Akiyoshi Ishiyama; Toshiyuki Yoshio; Toshiaki Hirasawa; Yorimasa Yamamoto; Tomohiro Tsuchida; Masahiro Igarashi; Toshifusa Nakajima; Hiroshi Takahashi
Journal:  Gastric Cancer       Date:  2014-12-10       Impact factor: 7.370

7.  Helicobacter pylori infection-negative gastric cancer in Japanese hospital patients: incidence and pathological characteristics.

Authors:  Shunji Kato; Norio Matsukura; Katsuya Tsukada; Noriko Matsuda; Tsutomu Mizoshita; Tetsuya Tsukamoto; Masae Tatematsu; Yuichi Sugisaki; Zenya Naito; Takashi Tajiri
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Journal:  Cancer       Date:  2009-05-15       Impact factor: 6.860

9.  Relationship of Helicobacter pylori to serum pepsinogens in an asymptomatic Japanese population.

Authors:  M Asaka; T Kimura; M Kudo; H Takeda; S Mitani; T Miyazaki; K Miki; D Y Graham
Journal:  Gastroenterology       Date:  1992-03       Impact factor: 22.682

10.  Pernicious anemia and subsequent cancer. A population-based cohort study.

Authors:  A W Hsing; L E Hansson; J K McLaughlin; O Nyren; W J Blot; A Ekbom; J F Fraumeni
Journal:  Cancer       Date:  1993-02-01       Impact factor: 6.860
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  4 in total

1.  Clinicopathological and molecular characterization of early gastric adenocarcinoma in Helicobacter pylori-uninfected patients: emphasis on differentiated gastric adenocarcinoma.

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2.  Helicobacter pylori-Negative Advanced Gastric Cancer Arising from the Gastric Mucosa without Inflammation, Atrophy, or Intestinal Metaplasia.

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3.  Endoscopic and histological features of Helicobacter pylori-negative differentiated gastric adenocarcinoma arising in the antrum.

Authors:  Maiko Takita; Ken Ohata; Rin Inamoto; Marie Kurebayashi; Syunya Takayanagi; Yoshiaki Kimoto; Yuichiro Suzuki; Rindo Ishii; Kohei Ono; Ryoju Negishi; Yohei Minato; Eiji Sakai; Takashi Muramoto; Nobuyuki Matsuhashi; Shin Ichihara
Journal:  JGH Open       Date:  2021-03-02

4.  Combined acupuncture and general anesthesia on immune and cognitive function in elderly patients following subtotal gastrectomy for gastric cancer.

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  4 in total

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